This review article addresses the history, underlying evidence, proposed mechanisms, and clinical implication ofsodium glucose cotransporter type 2 inhibitors (SGLT2i),framing them from the perspective of the general practitioner internist of the present decade. The sodium glucose cotransporter inhibitors, onceidentified in the apple tree root bark but with no obvioustherapeutic purpose, were initially develope...
Introduction and objectives: Heart failure (HF) is a complex clinical syndrome that is a significant burden in hospitalisations, morbidity, and mortality. Although a significant effort has been made to better understand its consequences and current barriers in its management, there are still several gaps to address. The present work aimed to identify the views of a multidisciplinary group of health care profess...
Heart failure (HF) is a serious burden for the public health in Portugal, being associated to high morbidity and mortality. The clinical management of HF is complex and the disease awareness and healthcare articulation need to be improved. HF patients are frequently hospitalized due to acute episodes. These hospital stays are excellent opportunities for the optimization of the HF clinical management. According ...
Introduction: Clinical presentation of spondylodiscitis is heterogeneous. Its diagnosis is sometimes challenging. The authors characterize and evaluate the prevalence of spondylodiscitis in a Department of Internal Medicine (DIM).Population/Methods: Observational retrospective study of allpatients with spondylodiscitis diagnosis at discharge from2007 to 2016. Demographic variables, presentation symptoms, risk f...