11 documents found, page 1 of 2
Crotacetin, a Novel Snake Venom C-Type Lectin Homolog of Convulxin, Exhibits an...
Rádis-Baptista, Gandhi; Moreno, Frederico Bruno Mendes Batista; Nogueira, Lucas de Lima; Martins, Alice M. C.; Toyama, Daniela de OliveiraSnake venom (sv) C-type lectins encompass a group of hemorrhagic toxins that are capable of interfering with blood stasis. A very well-studied svC-type lectin is the heterodimeric toxin, convulxin (CVX), from the venom of South American rattlesnake Crotalus durissus terrificus. CVX is able to activate platelets and induce their aggregation by acting via p62/GPVI collagen receptor. By using polymerase chain reac...
Bioaffinity fishing procedure using secretory phospholipase A2 for screening fo...
Toyama, Marcos Hikari
STRUCTURAL AND FUNCTIONAL COMPARISONS OF THE GPLI FROM VENOMOUS AND NON-VENOMOU...
Serino-Silva, Caroline; Bittencourt Rodrigues, Caroline Fabri; Grego, Kathleen Fernandes; Nogueira de Carvalho, Marcelo Pires; Toyama, Marcos HikariMade available in DSpace on 2020-12-10T17:37:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-04-20; Inst Butantan, Sao Paulo, Brazil; Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil; Univ Estadual Paulista, Sao Paulo, SP, Brazil; Univ Estadual Paulista, Sao Paulo, SP, Brazil
Anti-ophidian activity of Bredemeyera floribunda Willd. (Polygalaceae) root ext...
Alves, Natacha Teresa Queiroz; Ximenes, Rafael M.; Jorge, Roberta J. B.; Silveira, J. A. M.; Santos, J. V. A.; Rodrigues, F. A. P.; Costa, P. H. S.Bredemeyera floribunda roots are popularly used to treat snakebites in the semiarid region of Northeast Brazil, and previous studies indicate the anti-ophidian actions of triterpenoid saponins found in its roots. To assess B. floribunda root extract (BFRE) activity against the effects of Bothrops jararacussu venom (BjuV), antiphospholipasic, antiproteolytic, antihemorrhagic, antinecrotic, and anti-edematogenic ...
Evaluation of Rhamnetin as an Inhibitor of the Pharmacological Effect of Secret...
Toyama, Marcos Hikari
Purification and biological effects of a C-type lectin isolated from Bothrops m...
Barbosa, Paulo Sérgio Ferreira; Martins, Alice Maria Costa; Toyama, Marcos Hikari; Joazeiro, Paulo Pinto; Fonteles, Manassés ClaudinoSnake venom proteins from the C-type lectin family have very distinct biological activities despite their highly conserved primary structure, which is homologous to the carbohydrate recognition region of true C-type lectins. We purified a lectin-like protein (BmLec) from Bothrops moojeni venom and investigated its effect on platelet aggregation, insulin secretion, antibacterial activity, and isolated kidney cel...
Evaluation of potential thrombin inhibitors from the white mangrove (Laguncular...
Toyama, Marcos Hikari
An Evaluation of 3-Rhamnosylquercetin, a Glycosylated Form of Quercetin, agains...
Toyama, Marcos Hikari
Purification of a PHA-like chitin-binding protein from Acacia farnesiana seeds ...
Santi-Gadelha, Tatiane; Rocha, Bruno Anderson Matias; Oliveira, Cecília Carvalho; Aragão, Karoline Sabóia; Marinho, EEmmanuel SilvaA lectin-like protein from the seeds of Acacia farnesiana was isolated from the albumin fraction, characterized, and sequenced by tandem mass spectrometry. The albumin fraction was extracted with 0.5 M NaCl, and the lectin-like protein of A. farnesiana (AFAL) was purified by ion-exchange chromatography (Mono-Q) followed by chromatofocusing. AFAL agglutinated rabbit erythrocytes and did not agglutinate human ABO...
Miotoxinas PLA2 "like" de Bothrops pirajai : caracterização molecular e funcional
Toyama, Marcos HikariOrientador: Sergio Marangoni; Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia; Resumo: As serpentes do gênero Bothrops incluem várias espécies, que são amplamente distribuídas na América do Sul e do Norte. Entre as proteínas bioativas do veneno de Bothrops, as Fosfolipases Az (PLAz,E.c. 3.1.14) e as miotoxinas PLAz"like" destacam-se como seus componentes majoritários. Fosfolipases Az...