117 documents found, page 1 of 12
Intestinal mucosal alterations parallel central demyelination and remyelination...
Ferreira, Carolina; Carvalho, Filipa; Vieira, Pedro; Alves, André; Palavra, Filipe; Almeida, Jani; Alves, Vera; Coscueta, EzequielBackground: The gut-brain axis has been increasingly recognized as a critical factor in Multiple Sclerosis (MS) pathophysiology. While its role in demyelination is well documented, gut-brain axis involvement during remyelination remains largely unexplored. Methods: Using the cuprizone (CPZ) model, which induces reversible demyelination and spontaneous remyelination upon toxin withdrawal, we investigated gut and...
Polyphenols: immunonutrients tipping the balance of immunometabolism in chronic...
Ferreira, Carolina; Vieira, Pedro; Sá, Helena Manuel Pina de Oliveira e; Malva, João Oliveira; Castelo-Branco, MiguelMounting evidence progressively appreciates the vital interplay between immunity and metabolism in a wide array of immunometabolic chronic disorders, both autoimmune and non-autoimmune mediated. The immune system regulates the functioning of cellular metabolism within organs like the brain, pancreas and/or adipose tissue by sensing and adapting to fluctuations in the microenvironment's nutrients, thereby reshap...
Coverage and data rate analysis for a novel cell-sweeping-based RAN deployment
Borralho, Rúben; Quddus, Atta Ul; Mohamed, Abdelrahim; Vieira, Pedro; Tafazolli, RahimAdequate and uniform network coverage provision is one of the main objectives of cellular service providers. Additionally, the densification of cells exacerbates coverage and service provision challenges, particularly at the cell-edges. In this paper, we present a new approach of cell-sweeping-based Base Stations (BSs) deployments in cellular Radio Access Networks (RANs) where the coverage is improved by enhanc...
On the use of spatial graphs for performance degradation root-cause analysis to...
Mata, Luís; Sousa, Marco; Vieira, Pedro; Queluz, Maria Paula; Rodrigues, AntónioOn the road to the sixth generation of cellular networks (6G), the need to ensure a sustainable usage of natural resources, amid increased competition and cost pressures, has driven the adoption of text Self-Healing Mobile Networks to enhance operational efficiency of current and future wireless networks. This paradigm shift relies on Artificial Intelligence (AI) to increase automation of network functions, not...
Unraveling the root causes of faults in mobile communicatios: A comparative ana...
Cilínio, Madalena Ramos; Pereira, Márcio; Duarte, David; Mata, Luís; Vieira, PedroThe escalating demand and complexity of monitoring services handled by Network Operations Centers (NOCs) have led Mobile Network Operators (MNOs) to prioritize automated solutions for network fault detection and diagnosis. Consequently, various Machine Learning (ML)-based Root Cause Analysis (RCA) systems have been developed, however their lack of explainability poses a challenge due to the predominantly black-...
Effect of blueberry supplementation on a diet-induced rat model of prediabetes—...
Ferreira, Gonçalo; Vieira, Pedro; Alves, André; Nunes, Sara; Preguiça, Inês; Martins-Marques, Tânia; Ribeiro, Tânia; Girão, Henrique; Figueirinha, ArturBlueberries, red fruits enriched in polyphenols and fibers, are envisaged as a promising nutraceutical intervention in a plethora of metabolic diseases. Prediabetes, an intermediate state between normal glucose tolerance and type 2 diabetes, fuels the development of complications, including hepatic steatosis. In previous work, we have demonstrated that blueberry juice (BJ) supplementation benefits glycemic cont...
Robotic radiosurgery for temporal bone paragangliomas: single-center experience...
Ramos, Sofia; Simões , Sara; Amorim, Marina; Costa, Maria Adelina; Campos, Guilherme; Fonseca, Graça; Carvalho, Miguel; Vieira, Pedro; Calçada, CármenObjective: To report the experience of a single center in the treatment of temporal bone paragangliomas with Robotic Radiosurgery. Study Design: Single-center retrospective analysis Material and Methods: Between 2017 and 2021, 8 patients with temporal bone paragangliomas were treated with Cyberknife in the Department of Radiation Oncology of Instituto CUF Porto. Results: Half of the patients were diagnosed with...
Integration of visible light communication, artificial intelligence, and rerout...
Vieira, Manuela; Galvão, Gonçalo; Vieira, Manuel Augusto; Véstias, Mário; Vieira, Pedro; Louro, PaulaThis study combines Visible Light Communication (VLC) and Artificial Intelligence (AI) to enhance traffic signal control, reduce congestion, and improve safety, through real-time monitoring and dynamic traffic management. Leveraging VLC technology, the system uses existing road infrastructure to transmit live data on vehicle and pedestrian positions, speeds, and queues. AI agents, employing Deep Reinforcement L...
A machine learning driven methodology for alarm prediction towards self-healing...
Mata, Luís; Sousa, Marco; Vieira, Pedro; Queluz, Maria Paula; Rodrigues, AntónioAlthough Artificial Intelligence (AI) is already used by 5th Generation (5G) to support specific network functions, the increased complexity of 6th Generation (6G) will demand the adoption of extended AI capabilities to enhance network efficiency. Moreover, high network performance and availability at a sustainable cost will be crucial to emerging applications, such as autonomous vehicles and smart cities. In t...
TNFR2 as a Potential Biomarker for Early Detection and Progression of CKD
Lousa, Irina; Reis, Flávio; Viana, Sofia; Vieira, Pedro; Vala, Helena; Belo, Luís; Santos-Silva, AliceThe inflammatory pathway driven by TNF-α, through its receptors TNFR1 and TNFR2, is a common feature in the pathogenesis of chronic kidney disease (CKD), regardless of the initial disease cause. Evidence correlates the chronic inflammatory status with decreased renal function. Our aim was to evaluate the potential of TNF receptors as biomarkers for CKD diagnosis and staging, as well as their association with th...