21 documents found, page 1 of 3

Editorial: Neuroimaging in early intervention in psychiatry

Characterization of plasma SDS-protein aggregation profile of patients with hea...

This study characterizes the plasma levels and composition of SDS-resistant aggregates (SRAs) in patients with heart failure with preserved ejection fraction (HFpEF) to infer molecular pathways associated with disease and/or proteostasis disruption. Twenty adults (ten with HFpEF and ten age-matched individuals) were included. Circulating SRAs were resolved by diagonal two-dimensional SDS-PAGE, and their protein...

Anais do I Seminário Internacional de Ensino da Arte: cultura visual, escola e ...

Submitted by Simone Maisonave (simonemaisonave@hotmail.com) on 2020-12-30T01:46:46Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Anais_do_I_SIEA.pdf: 14663949 bytes, checksum: eead5d8b886724ec62782f0ab8bad7f1 (MD5); Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2020-12-30T22:41:57Z (GMT) No. of bitstreams: 2 Anais_do_I_SIEA.pdf: 1466...

PNI versus SCI: the acute neuronal-specific transcriptional responses after lesion

Spinal cord injury (SCI) has devastating functional consequences to patients, but lacks effective treatment. Peripheral nerve injury (PNI) is a widely used model to discover new regeneration associated genes (RAGs). Various transcriptomic studies have profiled injured spinal cord or sciatic nerve tissues aiming to discover new RAGs. However, it is difficult to depict neuronal-specific responses from whole-tissu...

Modulating protein aggregation in cell models using modified steroids

P rotein aggregation is a biological process in which misfolded proteins aggregate and accumulate in intra- or extracellular media. Protein aggregation is intimately linked to the pathogenesis of many neurodegenerative diseases (such as Alzheimer’s, Huntington, Parkinson’s and prion diseases) but also in cancer and cardiovascular pathologies (e.g. atherosclerosis, heart failure and ischemic heart disease).1 How...

Autoimmune hepatitis in 828 Brazilian children and adolescents: clinical and la...

sentation, laboratory findings, histological profile, treatments, and outcomes of children andadolescents with autoimmune hepatitis.Methods: The medical records of 828 children and adolescents with autoimmune hepatitiswere reviewed. A questionnaire was used to collect anonymous data on clinical presentation,biochemical and histological findings, and treatments.Results: Of all patients, 89.6% had autoimmune hepa...

Conflitos entre usuários e desenvolvedores de soluções informatizadas

Nesta tese, abordam-se conflitos entre usuários e desenvolvedores, gerados por soluções informatizadas que não atendem às expectativas do usuário, partindo do pressuposto de que esses conflitos decorrem de dificuldades comunicacionais em etapas que antecedem à elaboração da solução. Posto isso, propõe-se, como hipótese de trabalho, que a teoria de conciliação de metas de Rauen (2014), baseada em relações de rel...

Radiotherapy couches: is kevlar an obstacle? Attenuation study of three differe...

Introduction: Treatment tabletops are usually made of carbon fibre due to its high mechanical strength and rigidity, low specific density, extremely light and regularly considered radio translucent. Our clinic acquired a Calypso 4D Localization System where electromagnetic (EM) frequencies to detect implanted transponders in the patient are used. Carbon fibre is an electrical conductive material which interfere...

Proactive modeling of goals and elaboration of computerized solutions

Computerized solutions for solving concrete everyday problems are structured through deductive algorithms. However, even before designing algorithms, there is an abductive step guided by the goal to be achieved, which is usually neglected. Following Rauen’s (2014) Goal Conciliation Theory, I intend in this study to describe and explain the process of formulation, execution and checking of ante-factual abductive...

Calypso’s array attenuation

Introduction: The Calypso 4D Localization System gives the possibility to track the tumour during treatment, with no additional ionising radiation delivered. To monitor the patient continuously an array is positioned above the patient during the treatment. We intend to study, for various gantry angles, the attenuation effect of the array for 6- and 10 MV and flattening filter free (FFF) 6- and FFF 10 MV photon ...