2 documents found, page 1 of 1
A review of Cushing's disease treatment by the Department of Neuroendocrinology...
Machado, Márcio Carlos; Fragoso, Maria Candida Barisson Vilares; Moreira, Ayrton Custódio; Boguszewski, César Luiz; Vieira Neto, LeonardoThe treatment objectives for a patient with Cushing's disease (CD) are remission of hypercortisolism, adequate management of co-morbidities, restoration of the hypothalamic-pituitary-adrenal axis, preservation of fertility and pituitary function, and improvement of visual defects in cases of macroadenomas with suprasellar extension. Transsphenoidal pituitary surgery is the main treatment option for the majority...
An immunofluorescence test for diagnosis of ophthalmic herpes in a mouse cornea...
Pereira, Sílvia Regina Ferreira Gonçalves; Câmara, Fernando Portela; Guimarães, Maria Angélica Arpon Marandino; Vieira Neto, LeonardoHerpes simplex virus type 1 (HSV-1) ophthalmic disease is the most common cause of corneal blindness in humans world-wide. Current culture techniques for HSV take several days and commercially available HSV laboratory based diagnostic techniques vary in sensitivity. Our study was conducted to evaluate the use of a quicker and simpler method to herpes ophthalmic diagnosis. Corneal smears were made by firm imprin...