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Molecularly imprinted polymer-based sensor for the determination of 2,4-dinitro...

Torre, Ricarda; Rebelo, Patrícia; Seguro, Isabel; Pacheco, João G.; Amaral, Joana S.; Nouws, Henri P.A.; Delerue-Matos, Cristina

The rising demand for weight-loss solutions, driven by obesity concerns and societal pressure, has led to an increasing growth in both the consumption and market of food supplements. However, several studies have identified food supplements as common targets of economically motivated adulteration by the addition of pharmaceutical drugs to enhance the product's effects. Despite its toxicity and associated health...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Authenticating honey origin from Natural Park of Montesinho: innovative electro...

Pereira, Eduarda; Morais, Stephanie L.; Seguro, Isabel; Silva, Nádia F. D.; Santos, Marlene; Pacheco, João G.; Delerue-Matos, Cristina

The Natural Park of Montesinho (NPM) has a diverse ecosystem that is home to countless species of trees and plants characteristic of this area, including Castanea sativa. The honey produced in this region is highly appreciated for its taste and nutritional value, but it also has a wide range of health benefits. The geographical origin of the honey is a very important aspect in assessing the quality and authenti...


Electrochemical chemically based sensors and emerging enzymatic biosensors for ...

Caldevilla, Renato; Morais, Stephanie L.; Cruz, Agostinho; Delerue-Matos, Cristina; Moreira, Fernando; Pacheco, João G.; Santos, Marlene

Major depressive disorder is a widespread condition with antidepressants as the main pharmacological treatment. However, some patients experience concerning adverse reactions or have an inadequate response to treatment. Analytical chromatographic techniques, among other techniques, are valuable tools for investigating medication complications, including those associated with antidepressants. Nevertheless, there...


Molecularly imprinted electrochemical sensor prepared on a screen printed carbo...

Lopes, Frederico; Pacheco, João G.; Rebelo, Patrícia; Delerue-Matos, Cristina

Naloxone (NLX) is a pharmaceutical used as opioid antagonist. A molecular imprinted polymer elec-trochemical sensor for simple and rapid detection of NLX was prepared through the modification of commercial available screen printed carbon electrode (SPCE). The SPCE was modified with multi-walled carbon nanotubes (MWCNT) by drop coating to increase the signal response and improve the sensitiv-ity. The MIP preparati...


Molecularly imprinted electrochemical sensor for ochratoxin A detection in food...

Pacheco, João G.; Castro, Mafalda; Machado, Susana; Barroso, M. Fátima; Nouw, Henri P.A.; Delerue-Matos, Cristina

A novel electrochemical sensor for ochratoxin A (OTA) detection was fabricated through the modification of a glassy carbon electrode (GCE) with multiwalled carbon nanotubes (MWCNTs) and a molecularly imprinted polymer (MIP). The MWCNTs dramatically promoted the sensitivity of the developed sensor, while polypyrrole (PPy) imprinted with OTA served as the selective recognition element. The imprinted PPy film was ...


MIP-graphene-modified glassy carbon electrode for the determination of trimetho...

Silva, Hélder; Pacheco, João G.; Magalhães, Júlia Maria Coelho Santos; Viswanathan, Subramanian; Delerue-Matos, Cristina

A novel sensitive electrochemical sensor was developed by electropolymerization of pyrrole(PY)and molecularly imprinted polymer (MIP)which was synthesized onto a glassy carbon electrode (GCE) in aqueous solution using cyclic voltammetry in the presence of Trimethoprim (TMP) as template molecules. Furthermore,a previous electrode modification was performed by deposition of a suspension of graphene on the electro...


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