2 documents found, page 1 of 1
Risk Calculators in Bipolar Disorder: A Systematic Review
Silva Ribeiro, J; Pereira, D; Salagre, E; Coroa, M; Santos Oliveira, P; Santos, V; Madeira, N; Grande, I; Vieta, EIntroduction: Early recognition of bipolar disorder improves the prognosis and decreases the burden of the disease. However, there is a significant delay in diagnosis. Multiple risk factors for bipolar disorder have been identified and a population at high-risk for the disorder has been more precisely defined. These advances have allowed the development of risk calculators to predict individual risk of conversi...
A multi-centre, randomised, double-blind, placebo-controlled clinical trial of ...
Hegerl, U; Mergl, R; Sander, C; Dietzel, J; Bitter, I; Demyttenaere, K; Gusmão, R; González-Pinto, A; Zorrilla, I; Alocén, AG; Sola, VP; Vieta, EBased on many clinical and preclinical findings the ‘vigilance regulation model of mania’ postulates that an unstable regulation of wakefulness is a pathogenetic factor in both mania and Attention Deficit Hyperactivity Disorder (ADHD) and induces hyperactivity and sensation seeking as an autoregulatory attempt to stabilize wakefulness. Accordingly, stimulant medications with their vigilance stabilizing properti...