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Brazilian Society of Hepatology and Brazilian Society of Infectious Diseases Gu...
Ferraz,Maria Lucia; Strauss,Edna; Perez,Renata Mello; Schiavon,Leonardo; Ono,Suzane Kioko; Pessoa,Mario Guimarães; Ferreira,Adalgisa PaivaAbstract Chronic hepatitis B is an important health problem that can progress to cirrhosis and complications such as hepatocellular carcinoma. There is approximately 290 million of people with chronic hepatitis B virus (HBV) infection worldwide, however only 10% of patients are currently identified.Most part of Brazil is considered of low prevalence of HBV infection but there are some regions with higher freque...
Weight-based combination therapy with peginterferon alpha-2b and ribavirin for ...
Gonçales Jr.,Fernando Lopes; Vigani,Aline; Gonçales,Neiva; Barone,Antonio Alci; Araújo,Evaldo; Focaccia,Roberto; Oliveira,UmbelianaCombination therapy with pegylated interferon and ribavirin is considered the new standard therapy for naïve patients with chronic hepatitis C. We evaluated the efficacy and safety of treatment with weight-based peginterferon alpha-2b (1.5 mg/kg per week) plus ribavirin (800-1,200 mg/day) for 48 weeks in naïve, relapser and non-responder (to previous treatment with interferon plus ribavirin) patients with chron...