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Multiple sclerosis relapse incomplete recovery and associated factors – a syste...
Ladeira, Filipa; Soares, Mafalda; Faustino, Patrícia; Leal Rato, Miguel; Gomes, Inês; Caetano, André; Taipa, Ricardo; Sá, Maria JoséPublisher Copyright: © 2025; Objectives: We conducted a meta-analysis to assess the frequency of incomplete recovery from multiple sclerosis (MS) relapses and a systematic review to evaluate the influence of six factors on incomplete recovery: relapse severity, age, sex, disease duration, disease-modifying treatment use, and the presence of contrast-enhancing lesions at relapse. Methods: We searched Scientific ...
Motor cortex stimulation for refractory demyelinating disease-associated trigem...
Mendonça, Marcelo D; Seromenho-Santos, Alexandra; Caetano, André; Reizinho, CarlaPatients with demyelinating diseases (DDs) such as multiple sclerosis have a 20-fold higher risk of developing trigeminal neuralgia (TN). DD-related TN is more frequently refractory to the usual medical and surgical treatment. We report the case of a 57-year-old man presenting to our neurology outpatient clinic with a 12-year history of medical and surgical refractory TN associated with demyelinating lesions on...
Analysis of riluzole’s profile of use in a central hospital in Lisbon
Paróla, Ana; de Palhares Falcão, Fátima da Silva Mousinho; Farinha, Helena; Caetano, André; Santos, Luís; Medeiros, Elmira; Viana-Baptista, MiguelPurpose: Riluzole is indicated to prolong life or delay the institution of mechanical ventilation in patients with amyotrophic lateral sclerosis (ALS). Clinical studies have shown that this drug prolongs survival, defined as living patients who are not intubated for mechanical ventilation and without tracheotomy. The purpose of this study is to characterize riluzole’s use as well as the user population in order...
Letter to the Editor: Medication-Overuse Headache is Common in Portuguese Migra...
Duarte Mendonça, Marcelo; Caetano, André; Salavisa, Manuel; Viana-Baptista, Miguel; Miguel, Rita; Pinto, Miguel; Barbosa, Raquel; Ladeira, FilipaCarta ao Editor: A Cefaleia por Uso Excessivo de Medicação é Comum em Doentes Portugueses com Enxaqueca
Non-Motor symptoms in Portuguese Parkinson's Disease patients
Bugalho, Paulo; Lampreia, Tânia; Miguel, Rita; Sousa, Marcelo D.; Caetano, André; Barbosa, RaquelThe prevalence of non-motor symptoms (NMS) in Parkinson's Disease (PD) has varied between studies. Their interrelation isn't totally understood. Also, the relative importance of each symptom, regarding its impact on activities of daily living (ADL) and health related quality of life (HRQL), remains debatable. We assessed all PD patients attending a Portuguese tertiary movement disorders center during one year (...
Incomplete HANAC (Hereditary angiopathy, nephropathy, aneurysms, and muscle cra...
Caetano, André; Barbosa, Raquel; Costa, João; Viana-Baptista, MiguelBackground: The various phenotypes associated with COL4A1 gene mutations, originally associated with autossomal dominant porencephaly, have recently been expanded, accomodating presentations such as cerebral small vessel disease with intracranial hemorrhages; cerebral small vessel disease and Axenfeld-Rieger anomaly; and the HANAC (Hereditary Angiopathy with nephropathy, aneurysms and muscle cramps) syndrome. B...