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Gait characterization and analysis of hereditary amyloidosis associated with tr...

Vilas-Boas, Maria do Carmo; Fonseca, Pedro Filipe Pereira; Sousa, Inês Martins; Cardoso, Márcio Neves; Cunha, João Paulo Silva; Coelho, Teresa

Hereditary amyloidosis associated with transthyretin (ATTRv), is a rare autosomal dominant disease characterized by length-dependent symmetric polyneuropathy that has gait impairment as one of its consequences. The gait pattern of V30M ATTRv amyloidosis patients has been described as similar to that of diabetic neuropathy, associated with steppage, but has never been quantitatively characterized. In this study ...


iHandU: A Novel Quantitative Wrist Rigidity Evaluation Device for Deep Brain St...

Múrias Lopes, Elodie; Vilas-Boas, Maria do Carmo; Dias, Duarte; Rosas, Maria José; Vaz, Rui; Silva Cunha, João Paulo

Deep brain stimulation (DBS) surgery is the gold standard therapeutic intervention in Parkinson's disease (PD) with motor complications, notwithstanding drug therapy. In the intraoperative evaluation of DBS's efficacy, neurologists impose a passive wrist flexion movement and qualitatively describe the perceived decrease in rigidity under different stimulation parameters and electrode positions. To tackle this s...


Clinical 3-D Gait Assessment of Patients with Polyneuropathy Associated with He...

Vilas-Boas, Maria do Carmo; Rocha, Ana Patrícia; Cardoso, Márcio Neves; Fernandes, José Maria; Coelho, Teresa; Cunha, João Paulo Silva

Hereditary amyloidosis associated with transthyretin V30M (ATTRv V30M) is a rare and inherited multisystemic disease, with a variable presentation and a challenging diagnosis, follow-up and treatment. This condition entails a definitive and progressive motor impairment that compromises walking ability from near onset. The detection of the latter is key for the disease's diagnosis. The aim of this work is to per...


SnapKi—An Inertial Easy-to-Adapt Wearable Textile Device for Movement Quantific...

Oliveira, Ana; Dias, Duarte; Múrias Lopes, Elodie; Vilas-Boas, Maria do Carmo; Paulo Silva Cunha, João

The development of wearable health systems has been the focus of many researchers who aim to find solutions in healthcare. Additionally, the large potential of textiles to integrate electronics, together with the comfort and usability they provide, has contributed to the development of smart garments in this area. In the field of neurological disorders with motor impairment, clinicians look for wearable devices...


Full-body motion assessment: concurrent validation of two body tracking depth s...

Vilas-Boas, Maria do Carmo; Choupina, Hugo Miguel Pereira; Rocha, Ana Patrícia; Fernandes, José Maria; Cunha, João Paulo Silva

RGB-D cameras provide 3-D body joint data in a low-cost, portable and non-intrusive way, when compared with reference motion capture systems used in laboratory settings. In this contribution, we evaluate the validity of both Microsoft Kinect versions (v1 and v2) for motion analysis against a Qualisys system in a simultaneous protocol. Two different walking directions in relation to the Kinect (towards - WT, and...


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