201 documents found, page 1 of 21
Droplet counter-current chromatography of indole alkaloids from Tabernaemontana...
Lima Cardoso, Claudia Andrea [UNESP]; Vilegas, Wagner [UNESP]Made available in DSpace on 2022-04-28T19:54:52Z (GMT). No. of bitstreams: 0 Previous issue date: 1999-01-01; This paper reports the separation of the indole alkaloids from the benzene extract of the root barks of Tabernaemontana hilariana (Apocynaceae). The crude alkaloid fraction was fractionated by droplet counter-current chromatography using a low polarity mixture (hexane:ethyl acetate:ethanol:water). Nine ...
Application of a home‐made supercritical fluid extraction system to the study o...
Vilegas, Janete H. Y.; Lanças, Fernando M.; Vilegas, Wagner [UNESP]Made available in DSpace on 2022-04-29T08:46:53Z (GMT). No. of bitstreams: 0 Previous issue date: 1994-01-01; Using a home‐made supercritical fluid extraction (SFE) system, SFE‐CO2 extracts with chemical composition comparable to those of the essential oils obtained by a traditional steam distillation procedure were obtained from two Lauraceae samples. Both the steam distillation oils and the SFE‐CO2 extract of...
Effect of Byrsonima crassa and phenolic constituents on Helicobacter pylori-ind...
Bonacorsi, Cibele [UNESP]; Raddi, Maria Stella G. [UNESP]; da Fonseca, Luiz Marcos [UNESP]; Sannomiya, Miriam; Vilegas, Wagner [UNESP]Made available in DSpace on 2022-04-29T08:48:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-01-01; Byrsonima crassa Niedenzu (Malpighiaceae) is used in Brazilian folk medicine for the treatment of diseases related mainly to gastric ulcers. In a previous study, our group described the gastric protective effect of the methanolic extract from the leaves of B. crassa. The present study was carried out to...
The role of qualea multiflora on mammary tumour cells and immune system
Carli, Camila B. de A. [UNESP]; Quilles, Marcela Bassi [UNESP]; Vilegas, Wagner [UNESP]; Carlos, Iracilda Z. [UNESP]Made available in DSpace on 2022-04-29T08:49:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-09-01; Species of the genus Qualea are used by the Brazilian public as a natural anti-inflammatory. Based on this evidence, we evaluated the effects of terpene fractions (βF and TF) obtained from Qualea multiflora on nitric oxide production (Griess assay), cytokines (IL-1, IL-10, IL-12, and TNF-α) and the tran...
Effect of Qualea multiflora on macrophages and tumour cells
Carli, Camila B. de A. [UNESP]; Quilles, Marcela B. [UNESP]; Vilegas, Wagner [UNESP]; Carlos, Iracilda Z. [UNESP]Made available in DSpace on 2022-04-29T09:12:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-12-23; Species of the genus Qualea are used by the Brazilian people as a natural anti-inflammatory. Based on this evidence, we evaluated the effects of terpene fractions βF and TF (rich in β-sitosterol and terpenoids, respectively) obtained from Qualea multiflora on nitric oxide production, cytokines (IL-1, IL...
Esteroide e triterpenos de espécies de qualea-bioatividade sobre mycobacterium ...
Nasser, Ana Lucia Martiniano [UNESP]; Pavan, Fernando Rogério [UNESP]; Boralle, Nivaldo [UNESP]; Zocolo, Guilherme Julião [UNESP]Made available in DSpace on 2022-04-29T09:35:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-01-01; The chloroform extract of bark of the tropical tree Qualea parviflora (Vochysiaceae) was fractionated by column chromatography on silica gel, yielding triterpenes (lupeol, lupenone, betulin, epi-betulinic acid and friedelin) and a steroid (β-sitosterol). β-sitosterol, lupenone and lupeol were also ident...
UHPLC-(ESI)-HRMS and NMR-Based Metabolomics Approach to Access the Seasonality ...
Zanatta, Ana C. [UNESP]; Vilegas, Wagner [UNESP]; Edrada-Ebel, RuAngelieMade available in DSpace on 2022-04-29T08:30:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-06; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Seasonality is one of the major environmental factors that exert influence over the synthesis and accumulation of secondary metabolites in medicinal plants. The application of the metabolomics approach for quality control of plant extracts i...
Protective effect of flavonoids from Passiflora edulis Sims on diabetic complic...
Salles, Bruno César Correa; Leme, Krissia Caroline; da Silva, Marcelo Aparecido; da Rocha, Cláudia Quintino; Tangerina, Marcelo M P [UNESP]Made available in DSpace on 2022-04-29T08:35:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-07; OBJECTIVES: This study was carried out to evaluate the effects of flavonoids present in leaves of Passiflora edulis fruit on complications induced by diabetes in rats. METHODS: The extract of P. edulis leaf was obtained by 70% ethanol maceration. From the dry extract, the fractions were obtained by cons...
Novel transdermal bioadhesive surfactant-based system for release and solubilit...
Volpe-Zanutto, Fabiana; Fonseca-Santos, Bruno [UNESP]; McKenna, Peter E.; Paredes, Alejandro J; Dávila, José Luis; McCrudden, Maelíosa T. C.Made available in DSpace on 2022-04-29T08:35:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; Artemether (ART) and lumefantrine (LUM) are the gold standard antimalarial drugs used for the treatment of malaria in children and pregnant women. Typically, ART and LUM are delivered orally in the form of a combined tablet, however, the appropriateness of this route of administration for these drugs is...
Gastroprotective Effects of the Aqueous Extract from Taraxacum officinale in Ra...
Zanatta, Maria Eduarda D. C.; Miorando, Daniela; Stefller, Amanda M.; Roos, Nátali; Ernetti, Jackeline; Predebon, Ana Júlia; Lindemann, HeloísaMade available in DSpace on 2022-04-29T08:38:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Taraxacum officinale F.H. Wigg. belonging to the family Asteraceae is an edible medicinal plant distributed worldwide. This study aimed to determine the gastroprotective effects of aqueous extract of T. officinale (AETo) in rats using ultrasound, histological, and biochemical analyses. In this study, ga...