34 documents found, page 1 of 4
Development of a Liver-on-a-Chip platform for preclinical studies using numeric...
Carvalho, Violeta MenesesCancer remains a major global health challenge, with incidence and mortality rising at an alarming rate. Despite advances in developing targeted nanoformulations, many fail during clinical trials, largely due to the inability of traditional preclinical techniques to accurately predict their performance and toxicity. This highlights the urgent need for the development of novel preclinical models that can replica...
Computational and experimental advances in liver-on-a-chip technology for cance...
Carvalho, Violeta Meneses; Ferreira, Mariana; Rodrigues, Raquel O.; Teixeira, S. F. C. F.; Lima, Rui A.The integration of numerical simulations with Liver-on-a-Chip (LoC) technology ofers an innovative approach for studying liver physiology and pathology, especially in the context of liver cancer. Numerical simulations facilitate the optimization of microfuidic devices’ design and deepen the understanding of fuid fow and mass transfer. However, despite signifcant advancements, challenges such as replicating the ...
Advances in Microfluidic Systems and Numerical Modeling in Biomedical Applicati...
Ferreira, Mariana; Carvalho, Violeta Meneses; Ribeiro, J.E.; Lima, Rui A.; Teixeira, Senhorinha F.C.F.; Pinho, DianaThe evolution in the biomedical engineering field boosts innovative technologies, with microfluidic systems standing out as transformative tools in disease diagnosis, treatment, and monitoring. Numerical simulation has emerged as a tool of increasing importance for better understanding and predicting fluid-flow behavior in microscale devices. This review explores fabrication techniques and common materials of m...
Numerical evaluation and experimental validation of fluid flow behavior within ...
Carvalho, Violeta Meneses; Gonçalves, Inês M.; Rodrigues, Nelson; Sousa, Paulo; Pinto, Vânia; Minas, Graça; Kaji, Hirokazu; Shin, Su RyonBy combining biomaterials, cell culture, and microfluidic technology, organ-on-a-chip (OoC) platforms have the ability to reproduce the physiological microenvironment of human organs. For this reason, these advanced microfluidic devices have been used to resemble various diseases and investigate novel treatments. In addition to the experimental assessment, numerical studies of biodevices have been performed aim...
Advances in microfluidic systems and numerical modeling in biomedical applicati...
Ferreira, Mariana; Carvalho, Violeta Meneses; Ribeiro, João; Lima, Rui Alberto Madeira Macedo; Teixeira, S. F. C. F.; Pinho, DianaThe evolution in the biomedical engineering field boosts innovative technologies, with microfluidic systems standing out as transformative tools in disease diagnosis, treatment, and monitoring. Numerical simulation has emerged as a tool of increasing importance for better understanding and predicting fluid-flow behavior in microscale devices. This review explores fabrication techniques and common materials of m...
Advancing blood-brain barrier-on-a-chip models through numerical simulations
Carvalho, Violeta Meneses; Rodrigues, Raquel O.; Shin, Su Ryon; Lima, Rui; Teixeira, S. F. C. F.Researchers have placed engineered or natural tissues within microfuidic chips originating the so-called organ-on-a-chip (OoC) devices. With this technology, organ models can be subjected to phenomena that replicate the complex in vivo biological environment. Furthermore, the OoC devices constitute a more valuable, cost-efective and ethical option when compared to assays performed in animal models for disease r...
Getting contact to elderly associates through the ICT: an exploratory study
Martins, Guilherme; Carvalho, Violeta Meneses; Afecto, Carlota; Teixeira, S. F. C. F.; Rodrigues, Cristina Maria SantosInformation and Communication Technologies - ICT has become a crucial element in the daily life of modern societies. Nevertheless, the elderly population does not follow the evolution of this new digitized world at the same pace. Thus, is necessary to ICT answer the digital demands of older adults. For this purpose, their literacy issues, physical limitations, and motivation have to be understood. This work pre...
Different teaching methods: a step for student motivation
Teixeira, Inês Maria Baptista; Carvalho, Violeta Meneses; Rodrigues, Nelson José Oliveira; Ferreira, Ana Cristina; Teixeira, S. F. C. F.Teaching is made by providing students with theoretical lessons and giving them the basic concepts of a subject and potentiating further development. Although this is an important step, student learning differs, and they have difficulty in transposing their theoretical knowledge into real-world problems. To help them make a bridge between the two realities, practical activities are essential. However, due to cl...
A PBL experience with second-year students of industrial engineering
Carvalho, Violeta Meneses; Costa, Lino; Teixeira, S. F. C. F.; Rodrigues, Cristina Maria SantosIn the last years, teaching methods significantly evolved. Instead of traditional teaching, where the professor is the primary source of knowledge, nowadays, student-centered approaches, where they actively participate in their learning, have been increasingly used. These methods allow increasing the students’ motivation, interest, and engagement in the learning process. There are different ways of implementing...
Implementation of a digital transition process for the documentation of an alum...
Martins, Guilherme Sousa Silva; Carvalho, Violeta Meneses; Teixeira, S. F. C. F.; Rodrigues, Cristina Maria SantosOften consisting of stacks or boxes of disordered documents, stored in cabinets full of boxes and papers, files tend to be evaluated only as an administrative requirement. With the recognition of the importance of documentary memory, the opportunity arises for a new approach to this type of resource. Lean originated in the manufacturing industry, aiming to maximize customer value while minimizing waste. Ever si...