8 documents found, page 1 of 1
Elevated IgA and IL-10 levels in very-early-onset inflammatory bowel disease se...
Sandy,Natascha Silva; Marega,Lia Furlaneto; Bechara,Giane Dantas; Riccetto,Adriana Gut Lopes; Bonfim,Carmen; Vilela,Maria Marluce dos SantosABSTRACT Objective: To report two patients with very-early-onset inflammatory bowel disease (VEOIBD) secondary to interleukin-10 receptor (IL-10R) mutations, explore immunophenotyping data and plasma cytokine profile on these cases compared to healthy controls, and describe the phenotype of IL-10/IL-10R mutations based on a literature review. Case description: We report on two female infants referred to our ter...
Human Inborn Errors of Immunity (HIEI): predominantly antibody deficiencies (PA...
Vilela,Maria Marluce dos SantosAbstract Objective: This minireview gathers the scientific foundations of the literature on genetic errors in the development of the humoral immune system to help pediatricians suspect these defects. Sources: A systemic search using the PubMed MEDLINE database was performed for all Predominantly Antibody Deficiencies (PADs) described in the 2020 IUIS Expert Committee for PID classification system, combined with...
Quality of sleep and quality of life in adolescents infected with human immunod...
Gazini,Carina Caires; Reimão,Rubens Nelson do Amaral Assis; Rossini,Sueli Regina Gottochilich; Centeville,Maraisa; Mazzola,Tais NitschOBJECTIVES: To assess sleep characteristics of adolescents infected by HIV, and to ascertain whether psychosocial aspects are associated to the quality of sleep. METHODS: A cross-sectional study assessing 102 HIV-infected adolescents of both genders, aged between 10 and 20 years-old and 120 Controls. Data collection was performed by applying the Sleep Disturbance Scale for Children, the Epworth Sleepiness Scale...
Partial chemical and functional characterization of milk whey products obtained...
Ziegler,Fabiane La Flor; Castro,Georgia Alvares; Moreno,Yara Maria Franco; Oya,Vanessa; Vilela,Maria Marluce dos Santos; Sgarbieri,Valdemiro CarlosWhey protein samples (S-1 to S-5) were tested in vivo and in vitro for nutritional properties and selected bioactivities. Weanling male Wistar rats fed modified AIN-93G (12 g protein.100 g-1) diets for 21 days were used the in vivo studies. The nutritional parameters did not differ among the protein diets tested. Erythrocyte glutathione content was considered high and was higher for S-3, but liver glutathione w...
Usefulness of pharmacy dispensing records in the evaluation of adherence to ant...
Ernesto,Aline Santarem; Lemos,Renata Muller Banzato Pinto de; Huehara,Maria Ivone; Morcillo,André Moreno; Vilela,Maria Marluce dos SantosINTRODUCTION: Adherence, which is crucial to the success of antiretroviral therapy (HAART), is currently a major challenge in the care of children and adolescents living with HIV/AIDS. OBJECTIVE: To evaluate the prevalence of nonadherence to HAART using complementary instruments in a cohort of children and adolescents with HIV/AIDS followed in a reference service in Campinas, Brazil. METHODS: The level of adher...
Hepatotoxicity in HIV-infected children and adolescents on antiretroviral therapy
Gil,Ana Cecília Montes; Lorenzetti,Raquel; Mendes,Gun Bergsten; Morcillo,André Moreno; Toro,Adyléia Aparecida Dalbo ContreraCONTEXT AND OBJECTIVE: Adverse drug reactions are a significant problem in patients on antiretroviral therapy (ART). We determined liver enzyme elevation frequencies in HIV-infected children and adolescents receiving ART, and their association with risk factors. DESIGN AND SETTING: Cross-sectional study, at the Pediatrics Immunodeficiency Division, University Hospital, Universidade Estadual de Campinas. METHODS...
Lack of association between nutritional status and change in clinical category ...
Centeville,Maraisa; Morcillo,André Moreno; Barros Filho,Antonio de Azevedo; Silva,Marcos Tadeu Nolasco da; Toro,Adyléia Aparecida Dalbo ContreraCONTEXT AND OBJECTIVE: Malnutrition is common among HIV-infected children. Our objective was to study the occurrence of malnutrition and its relationship with changes in clinical category among HIV-infected children. DESIGN AND SETTING: Longitudinal study, at the Pediatrics Department and Pediatrics Investigation Center (CIPED), Faculdade de Ciências Médicas da Universidade Estadual de Campinas (Unicamp). METHO...
Evolution of nutritional status of infants infected with the human immunodefici...
Leandro-Merhi,Vânia Aparecida; Vilela,Maria Marluce dos Santos; Silva,Marcos Nolasco da; Lopez,Fábio Ancona; Barros Filho,Antônio de AzevedoCONTEXT: There are today only a limited number of studies defining growth parameters and nutritional status for HIV children. OBJECTIVE: To study the nutritional status of infants infected with the human immunodeficiency virus. TYPE OF STUDY: Longitudinal study. SETTING: Department of Pediatrics, Faculty of Medical Sciences, UNICAMP, Campinas, Brazil. PARTICIPANTS: One hundred and twenty-four children born to H...