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Antifungal activity of liriodenine on clinical strains of Cryptococcus neoforma...

Levorato-Vinche,Adriele Dandara; Melhem,Marcia de Souza Carvalho; Bonfietti,Lucas Xavier; de-la-Cruz-Chacón,Iván; Boaro,Carmen Sílvia Fernandes

Abstract Background: Cryptoccocal meningitis continues to present high incidence among AIDS patients. The treatment of choice is the synergistic combination of flucytosine (5-FC) with amphotericin B deoxycholate (AmBd) or its lipid formulations. However, 5-FC is unavailable in many countries and AmB demands hospitalization. The combination of AmB with the fungistatic fluconazole (FLC) or the use of high FLC dai...

Data: 2022   |   Origem: Oasisbr

Impact of laryngeal sequelae on voice- and swallowing-related outcomes in parac...

Pissurno,Neisa Santos Carvalho Alves; Esteves,Lucas da Motta; Benedito,Juliana Marques; Giglio,Vanessa Ponsano; Carvalho,Lídia Raquel de

Abstract Background: The present study was carried out aiming to evaluate the impact of laryngeal sequelae on the quality of life of treated paracoccidioidomycosis (PCM) patients. Methods: This cross-sectional study was conducted at the Otorhinolaryngology Outpatient Clinic of the University Hospital, Federal University of Mato Grosso do Sul, Brazil. Thirty-two PCM patients considered clinically and immunologic...

Data: 2020   |   Origem: Oasisbr

Ultrasound dynamics of gastric content volumes after the ingestion of coconut w...

Carmona,Bruno Mendes; Almeida,Clauber Claudino Alves; Vieira,Waldônio de Brito; Fascio,Mario de Nazareth Chaves; Carvalho,Lídia Raquel de

Abstract Background: Adequate preoperative fasting is critical in preventing pulmonary aspiration of gastric content. We proposed to study the sonographic gastric content dynamics after the ingestion of liquid or solid food in healthy volunteers and confront it with current guidelines for preoperative fasting times. Methods: We performed a prospective, crossover, evaluator-blinded study involving 17 healthy vol...

Data: 2018   |   Origem: Oasisbr

Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-ind...

Lemos Neto,Sylvio Valença de; Vianna,Isabela Galvão; Castiglia,Yara Marcondes Machado; Golim,Marjorie de Assis; Souza,Aparecida Vitória Gonçalves de

Abstract Purpose: To investigate the effects of cyclosporine A on renal ischemia-reperfusion injury during transient hyperglycemia in rats. Methods: In a model of ischemia-reperfusion-induced renal injury and transiently induced hyperglycemia by intraperitoneal injection of glucose, 2.5 g.kg-1, Wistar rats were anesthetized with either isoflurane or propofol and received intravenous cyclosporine A, 5 mg.kg-1, f...

Data: 2017   |   Origem: Oasisbr

Noradrenaline and dobutamine effects on the volume expansion with normal saline...

Ramalho,Gualter Lisboa; Vane,Matheus Fachini; Lima,Luciana Cavalcanti; Vane,Lucas Fachini; Amorim,Rosa Beatriz; Domingues,Maria Aparecida

ABSTRACT PURPOSE: To evaluate the effects of dobutamine (DB), noradrenaline (NA), and their combination (NADB), on volume retention in rabbits submitted to hemorrhage. METHODS: Thirty six rabbits were randomly divided into 6 groups: SHAM, Control, Saline, DB, NA, DB+NA. All the animals, except for SHAM, were subjected to hemorrhage of 25% of the calculated blood volume. Control animals were replaced with their ...

Data: 2016   |   Origem: Oasisbr

Métodos eletrocardiográficos em equinos American Miniature Horse

Dantas,Gabriela Nascimento; Lourenço,Maria Lucia Gomes; Santarosa,Bianca Paola; Ulian,Carla Maria Vela; Heckler,Marta Cristina Thomas

O objetivo deste estudo foi analisar e comparar os registros eletrocardiográficos de 50 equinos American Miniature Horse, clinicamente saudáveis, obtidos pelos métodos convencional e computadorizado, para a padronização do método informatizado. As medidas de duração e amplitude das ondas e intervalos e frequência cardíaca foram analisadas nas derivações do plano frontal e na derivação base-ápice. Diferenças qua...

Data: 2015   |   Origem: Oasisbr

Inflection and stability points of diphasic logistic analysis of growth

Mischan,Martha Maria; Passos,José Raimundo de Souza; Pinho,Sheila Zambello de; Carvalho,Lídia Raquel de

Growth functions with inflection points following a diphasic model, can be adjusted by two approaches using segmented regression or the sum of two functions. In both cases, there are two functions, one for each phase, with inflection and stability points. However, when they are summed, the result is a new function and the points of inflection and stability are different from those obtained from using each funct...

Data: 2015   |   Origem: Oasisbr

Critical points on growth curves in autoregressive and mixed models

Pinho,Sheila Zambello de; Carvalho,Lídia Raquel de; Mischan,Martha Maria; Passos,José Raimundo de Souza

Adjusting autoregressive and mixed models to growth data fits discontinuous functions, which makes it difficult to determine critical points. In this study we propose a new approach to determine the critical stability point of cattle growth using a first-order autoregressive model and a mixed model with random asymptote, using the deterministic portion of the models. Three functions were compared: logistic, Gom...

Data: 2014   |   Origem: Oasisbr

Does propofol and isoflurane protect the kidney against ischemia/reperfusion in...

Carraretto,Antônio Roberto; Vianna Filho,Pedro Thadeu Galvão; Castiglia,Yara Marcondes Machado; Golim,Marjorie de Assis

PURPOSE: To study the effect of isoflurane (Iso) or propofol (Prop) anesthesia on renal ischemia/reperfusion injury (IRI) during transient hyperglycemia. METHODS: Thirty six rats were randomly assigned into six groups of six animals each: PHS (Sham-Prop=1mg.kg-1.min-1 + Hyperglycemia=2.5g.kg-1 of glucose solution administered intraperitoneally); HIS (Sham-Iso + Hyperglycemia); PHI (Prop + Hyperglycemia + Ischem...

Data: 2013   |   Origem: Oasisbr

Feedback de usuários como subsídio para avaliação do estudante de medicina

Hamamoto Filho,Pedro Tadao; Oliveira,Cristiano Claudino; Silva,Ludmila Almeida; Carvalho,Lídia Raquel de; Peraçoli,José Carlos

A avaliação é fundamental para o processo ensino-aprendizagem. Diferentes métodos de avaliação e diversos atores envolvidos na avaliação podem fornecer elementos distintos, que, somados, fornecem melhor compreensão sobre a efetividade do processo educacional em suas variadas dimensões. A avaliação de habilidades e atitudes de estudantes tem recebido grande atenção recentemente. O envolvimento de pacientes no pr...

Data: 2012   |   Origem: Oasisbr

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