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An Artificial Intelligence Approach to Thrombophilia Risk
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThrombophilia stands for a genetic or an acquired tendency to hypercoagulable states, frequently as venous thrombosis. Venous thromboembolism, represented mainly by deep venous thrombosis and pulmonary embolism, is often a chronic illness, associated with high morbidity and mortality. Therefore, it is crucial to identify the cause of the disease, the most appropriate treatment, the length of treatment or preven...
A Case Base View of Heart Failure Predisposition Risk
Vicente, Henrique; Martins, M. Rosário; Duarte, Margarida; Miguel, Patrícia; Grañeda, José M.; Caldeira, Filomena; Vilhena, João; Neves, JoãoHeart failure stands for an abnormality in cardiac structure or function which results in the incapability of the heart to deliver oxygen at an ideal rate. This is a worldwide problem of public health, characterized by high mortality, frequent hospitalization and reduced quality of life. Thus, this work will focus on the development of a decision support system to assess heart failure predisposing risk. The fra...
An Integrated Soft Computing Approach to Hughes Syndrome Risk Assessment
Vilhena, João; Martins, M. Rosário; Vicente, Henrique; Grañeda, José M.; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThe AntiPhospholipid Syndrome (APS) is an acquired autoimmune disorder induced by high levels of antiphospholipid antibodies that cause arterial and veins thrombosis, as well as pregnancy-related complications and morbidity, as clinical manifestations. This autoimmune hypercoagulable state, usually known as Hughes syndrome, has severe consequences for the patients, being one of the main causes of thrombotic dis...
An Artificial Intelligence Approach to Thrombophilia Risk
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José M.; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThrombophilia stands for a genetic or an acquired tendency to hypercoagulable states, frequently as venous thrombosis. Venous thromboembolism, represented mainly by deep venous thrombosis and pulmonary embolism, is often a chronic illness, associated with high morbidity and mortality. Therefore, it is crucial to identify the cause of the disease, the most appropriate treatment, the length of treatment or preven...
Antiphospholipid Syndrome Risk Evaluation
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José M.; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThe antiphospholipid syndrome is an acquired autoimmune disorder produced by high titers of antiphospholipid antibodies that cause both arterial and veins thrombosis as well as pregnancy-related complications and morbidity, as clinical manifestations. This autoimmune hypercoagulable state, often associated with coronary artery disease and recurrent Acute Myocardium Infraction, has severe consequences for the pa...
A case-based reasoning view of thrombophilia risk
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThrombophilia stands for a genetic or an acquired tendency to hypercoagulable states that increase the risk of venous and arterial thromboses. Indeed, venous thromboembolism is often a chronic illness, mainly in deep venous thrombosis and pulmonary embolism, requiring lifelong prevention strategies. Therefore, it is crucial to identify the cause of the disease, the most appropriate treatment, the length of trea...
A Soft Computing Approach to Acute Coronary Syndrome
Vicente, Henrique; Martins, M. Rosário; Mendes, Teresa; Vilhena, João; Grañeda, José; Gusmão, Rodrigo; Neves, JoséAcute Coronary Syndrome (ACS) is transversal to a broad and heterogeneous set of human beings, and assumed as a serious diagnosis and risk stratification problem. Although one may be faced with or had at his disposition different tools as biomarkers for the diagnosis and prognosis of ACS, they have to be previously evaluated and validated in different scenarios and patient cohorts. Besides ensuring that a diagn...
A Soft Computing Approach to Kidney Diseases Evaluation
Neves, José; Martins, M. Rosário; Vilhena, João; Neves, João; Gomes, Sabino; Abelha, António; Machado, José; Vicente, HenriqueKidney renal failure means that one’s kidney have unexpectedly stopped functioning, i.e., once chronic disease is exposed, the presence or degree of kidney dysfunction and its progression must be assessed, and the underlying syndrome has to be diagnosed. Although the patient’s history and physical examination may denote good practice, some key information has to be obtained from valuation of the glomerular filt...
Thrombophilia Screening – An Artificial Neural Network Approach
Vilhena, João; Martins, M. Rosário; Vicente, Henrique; Nelas, Luís; Machado, José; Neves, JoséThrombotic disorders have severe consequences for the patients and for the society in general, being one of the main causes of death. These facts reveal that it is extremely important to be preventive; being aware of how probable is to have that kind of syndrome. Indeed, this work will focus on the development of a decision support system that will cater for an individual risk evaluation with respect to the sur...
An assessment of chronic kidney diseases
Neves, José; Rosário Martins, M.; Vilhena, João; Neves, João; Gomes, Sabino; Abelha, António; Machado, José Manuel; Vicente, HenriqueKidney renal failure means that one’s kidney have unexpectedlystoppedfunctioning,i.e.,oncechronicdiseaseis exposed, the presence or degree of kidney dysfunction and its progression must be assessed, and the underlying syndrome has to be diagnosed. Although the patient’s history and physical examination may denote good practice, some key information has to be obtained from valuation of the glomerular filtration ...