Objective: To describe the quality of life of people with HIV/hepatitis C coinfection. Method: Systematic review guided by the question "How is the quality of life of people living with HIV//hepatitis C coinfection?" The PECO strategy was used to select descriptors in Portuguese, English, and Spanish, allowing the bibliographic search in April 2021 in the Embase, Scopus, PubMed, CINAHL, Academic Search Premier,...