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Nanoencapsulation of Gla-Rich Protein (GRP) as a Novel Approach to Target Infla...

Viegas, Carla S. B.; Araújo, Nuna; Carreira, Joana; Pontes, Jorge F.; Macedo, Anjos L.; Vinhas, Maurícia; Moreira, Ana S.; Faria, Tiago Q.; Grenha, Ana

LA/P/0101/2020 LA/P/0140/2020 AAC nº 41/ALG/2020—Project nº 072583—NUTRISAFE; Chronic inflammation is a major driver of chronic inflammatory diseases (CIDs), with a tremendous impact worldwide. Besides its function as a pathological calcification inhibitor, vitamin K-dependent protein Gla-rich protein (GRP) was shown to act as an anti-inflammatory agent independently of its gamma-carboxylation status. Although ...


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