3 documents found, page 1 of 1
Global guideline for the diagnosis and management of candidiasis: an initiative...
Cornely, Oliver A.; Sprute, Rosanne; Bassetti, Matteo; Chen, Sharon C-A; Groll, Andreas H.; Kurzai, Oliver; Lass-Flörl, CorneliaCandida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidiasis primarily affect patients who are immunocompromised or critically ill. In contrast, mucocutaneous forms of candidiasis, such as oral thrush and vulvovaginal candidiasis, can occur in otherwise healthy individual...
Community versus academic hospital community-acquired pneumonia patients: a nes...
Tsang, Jennifer L. Y.; Rego, Kian; Binnie, Alexandra; Binnie, Alexandra; Lee, Terry; Mccarthy, Anne; Cowan, Juthaporn; Archambault, PatrickBackground: Most Canadians receive their care in community hospitals, yet most clinical research is conducted in academic hospitals. This study aims to compare patients with community acquired pneumonia (CAP) treated in academic and community hospitals with respect to their demographics, clinical characteristics, treatments and outcomes. Methods This nested observational cohort substudy of the Community Acquire...
Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neu...
Bastard, Paul; Vazquez, Sara E.; Liu, Jamin; Laurie, Matthew T.; Wang, Chung Yu; Gervais, Adrian; Le Voyer, Tom; Bizien, Lucy; Zamecnik, ColinLife-threatening "breakthrough" cases of critical COVID-19 are attributed to poor or waning antibody (Ab) response to SARS-CoV-2 vaccines in individuals already at risk. Preexisting auto-Abs neutralizing type I IFNs underlie at least 15% of critical COVID-19 pneumonia cases in unvaccinated individuals; their contribution to hypoxemic breakthrough cases in vaccinated people is unknown. We studied a cohort of 48 ...