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Changes in Microbiota Profile in the Proximal Remnant Intestine in Infants Unde...

Barreiros-Mota, I; R. Araújo, J; Marques, C; Sousa, L; Morais, J; Castela, I; Faria, A; Neto, MT; Cordeiro-Ferreira, G; Virella, D; Pita, A

Early-life gut dysbiosis has been associated with an increased risk of inflammatory, metabolic, and immune diseases later in life. Data on gut microbiota changes in infants undergoing intestinal surgery requiring enterostomy are scarce. This prospective cohort study examined the enterostomy effluent of 29 infants who underwent intestinal surgery due to congenital malformations of the gastrointestinal tract, nec...


Individualized Fortification Based on Measured Macronutrient Content of Human M...

Cardoso, M; Virella, D; Papoila, AL; Alves, M; Macedo, I; e Silva, D; Pereira-da-Silva, L

The optimal method for human milk (HM) fortification has not yet been determined. This study assessed whether fortification relying on measured HM macronutrient content (Miris AB analyzer, Upsala, Sweden) composition is superior to fortification based on assumed HM macronutrient content, to optimize the nutrition support, growth, and body composition in infants born at <33 weeks' gestation. In a mixed-cohort st...



Clinical, Molecular Characterization and Long-Term Follow-Up of a Patient with ...

Padeira, G; Cavaco, BM; Virella, D; Sá-Couto, H; Lopes, ML

Heterozygous inactivating pathogenic variants of the calcium-sensing receptor encoding gene cause autosomal dominant familial hypocalciuric hypercalcemia, whereas mutations that inactivate both alleles cause neonatal severe hyperparathyroidism, a rare and potentially fatal disease. We present the clinical and genetic characterization of a Portuguese family with familial hypocalciuric hypercalcemia/neonatal seve...


Assessing the Risk for Falls Among Portuguese Community-Dwelling Stroke Survivo...

Pimenta, C; Correia, A; Alves, M; Virella, D

Purpose: This study assesses the estimation of the risk for falls among community-dwelling stroke survivors referred for ambulatory physiotherapy and explores factors that affect the risk. Methods: Observational, cross-sectional with nested case-control study, of individuals, referred to physiotherapy less than 12 months after stroke and able to walk independently. Berg Balance Scale, Timed Up and Go Test, and ...


Customized Human Milk Fortification Based on Measured Human Milk Composition to...

Cardoso, M; Virella, D; Macedo, I; Silva, Diana; Pereira da Silva, L

Adequate nutrition of very preterm infants comprises fortification of human milk (HM), which helps to improve their nutrition and health. Standard HM fortification involves a fixed dose of a multi-nutrient HM fortifier, regardless of the composition of HM. This fortification method requires regular measurements of HM composition and has been suggested to be a more accurate fortification method. This observation...


O Que Faz o Pediatra Ser Neonatologista

Pita, A; Matos, C; Virella, D; Proença, E; Negrão, F; Mimoso, G; Soares, H; Lapa, P; Barroso, R



Customized Human Milk Fortification Based on Measured Human Milk Composition to...

Cardoso, M; Virella, D; Macedo, I; Silva, D; Pereira-da-Silva, L

Adequate nutrition of very preterm infants comprises fortification of human milk (HM), which helps to improve their nutrition and health. Standard HM fortification involves a fixed dose of a multi-nutrient HM fortifier, regardless of the composition of HM. This fortification method requires regular measurements of HM composition and has been suggested to be a more accurate fortification method. This observation...


Better Balance: a Randomised Controlled Trial of Oculomotor and Gaze Stability ...

Correia, A; Pimenta, C; Alves, M; Virella, D

Objective: To assess the effect of a domiciliary program of oculomotor and gaze stability exercises on the incidence of falls and risk of fall in stroke survivors. Design: Two-arm, non-blinded parallel randomized controlled trial. Subjects: Stroke survivors older than 60 years, with positive Romberg test and autonomous gait after the stroke. Setting: Physiotherapy outpatient clinic of a tertiary care hospital. ...


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