4 documents found, page 1 of 1
Post-tuberculosis lung disease: a comparison of Brazilian, Italian, and Mexican...
Silva,Denise Rossato; Freitas,Alana Ambos; Guimarães,Amanda Reis; D’Ambrosio,Lia; Centis,Rosella; Muñoz-Torrico,Marcela; Visca,DinaABSTRACT Objective: To evaluate lung function in a cohort of patients with a history of pulmonary tuberculosis in Brazil, as well as to evaluate the decline in lung function over time and compare it with that observed in similar cohorts in Mexico and Italy. Methods: The three cohorts were compared in terms of age, smoking status, pulmonary function test results, six-minute walk test results, and arterial blood ...
Time course of exercise capacity in patients recovering from COVID-19-associate...
Zampogna,Elisabetta; Ambrosino,Nicolino; Saderi,Laura; Sotgiu,Giovanni; Bottini,Paola; Pignatti,Patrizia; Centis,Rosella; Migliori,Giovanni BattistaABSTRACT Objective: High prevalences of muscle weakness and impaired physical performance in hospitalized patients recovering from COVID-19-associated pneumonia have been reported. Our objective was to determine whether the level of exercise capacity after discharge would affect long-term functional outcomes in these patients. Methods: From three to five weeks after discharge from acute care hospitals (T0), pat...
Managing severe tuberculosis and its sequelae: from intensive care to surgery a...
Tiberi,Simon; Torrico,Marcela Muñoz; Rahman,Ananna; Krutikov,Maria; Visca,Dina; Silva,Denise Rossato; Kunst,Heinke; Migliori,Giovanni BattistaABSTRACT Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) continue to challenge physicians and public health specialists. Global treatment outcomes continue to be unsatisfactory, positive outcomes being achieved in only 54% of patients. Overall outcomes are even worse in patients infected with highly resistant strains. Treating MDR-/XDR-TB is difficult because of fr...
New and repurposed drugs to treat multidrug- and extensively drug-resistant tub...
Silva,Denise Rossato; Dalcolmo,Margareth; Tiberi,Simon; Arbex,Marcos Abdo; Munoz-Torrico,Marcela; Duarte,Raquel; D’Ambrosio,Lia; Visca,DinaABSTRACT Multidrug-resistant and extensively drug-resistant tuberculosis (MDR-TB and XDR-TB, respectively) continue to represent a challenge for clinicians and public health authorities. Unfortunately, although there have been encouraging reports of higher success rates, the overall rate of favorable outcomes of M/XDR-TB treatment is only 54%, or much lower when the spectrum of drug resistance is beyond that of...