67 documents found, page 1 of 7

Biomonitorização humana e genotoxicidade ambiental: quatro décadas de investiga...

Evaluation of the cyto- and genotoxicity of two types of cellulose nanomaterial...

Emerging cellulose nanomaterials (CNMs) may have commercial impacts in multiple sectors, being their application particularly explored in the food sector. Thus, their potential adverse effects in the gastrointestinal tract should be evaluated before marketing. This work aimed to assess the safety of two CNMs (CNF–TEMPO and CMF–ENZ) through the investigation of their cytotoxicity, genotoxicity (comet and micronu...

Normalização em Nanotecnologias SC1 – Terminologia e Nomenclatura

Definição e desenvolvimento de terminologia e nomenclatura inequívoca e uniforme no domínio das nanotecnologias, para facilitar a comunicação e promover o entendimento comum, entre as organizações e os indivíduos na indústria e aqueles que com eles interagem.

Avaliação da Segurança de Nanomateriais de Celulose Inovadores

Introdução: Na sociedade atual verifica-se uma preocupação acrescida com a exposição humana a materiais que, embora previamente considerados seguros, poderão revelar-se perigosos para a saúde quando usados à nanoescala. Este poderá ser o caso dos nanomateriais de celulose (CNMs), produzidos de fontes naturais, explorados para diversas aplicações, em particular na indústria alimentar. Podem ser usados como aditi...

Investigating ingested nanomaterials’ safety – the case of TiO2 and innovative ...

Introduction: The development of nanomaterials(NMs)-based technologies led to their increased use in key sectors and products related to food, food contact materials and feed. Many available products have NMs, as intentional constituents or contaminants from process ou food packaging release, such as silicon or titanium dioxide(TiO2) NMs. Others are being developed, like nanocelluloses(CNMs; doi:10.3390/nano121...

Efeitos da aflatoxina B1 na integridade e morfologia de células intestinais

Investigation of In Vitro Cytotoxicity and Genotoxicity of Novel Cellulose Nano...

Cellulose nanomaterials (CNMs) have been developed for applications in multiple food-related products, as food additives (e.g. stabilizers or thickeners), non-caloric fiber sources, or substitutes for petroleum-based food packaging materials(1,2). This work aimed to contribute for the safety assessment of two micro/nanofibrillated celluloses (CMF/CNFs), synthetized from industrial Eucalyptus globulus kraft. Bas...

In Vitro Cytotoxicity and Genotoxicity Assessment of Novel Cellulose Nanomateri...

Cellulose nanomaterials (CNMs) have been investigated for several applications, including in food and food packaging (e.g. as candidates for zero-calorie filler/thickener/stabilizers; as substitutes of petroleum-based food packaging materials). The widening of these applications will lead to human exposure via oral route, and potentially, to adverse health outcomes. To contribute to the CNMs safety evaluation, ...

Global DNA methylation and Reactive Oxygen Species assessment after in vitro ex...

Innovative cellulose nanomaterials (CNMs) find applications in multiple food-related products. However, it is recognized that nanomaterials (NMs) may cause adverse effects frequently by biological mechanisms that include production of intrinsic reactive oxygen species (ROS), or epigenetic alterations, by changes in gene expression through alterations in DNA methylation. To contribute to the safety assessment of...

Investigation of the genotoxicity of digested titanium dioxide nanomaterials in...

About Investigation of the genotoxicity of digested titanium dioxide nanomaterials in human intestinal cells