43 documents found, page 1 of 5
Teaching Quality at IHMT-NOVA: monitoring instruments for the period 2019 - 2024
Oliveira Martins, Maria do Rosário; Viveiros, Miguel; Abrantes, PatríciaIntroduction: The evaluation of teaching quality is one of the fundamental components of the Instituto de Higiene e Medicina Tropical da Universidade Nova de Lisboa's (IHMT-NOVA) pedagogical strategy and is anchored in the objectives of the NOVA Quality Council. This article describes the trend of the main Teaching Quality Indicators based on data collected between the 2019/2020 and 2023/2024 academic years at ...
Biomedicine and Artificial Intelligence in Postgraduate Education in Health Sci...
Viveiros, Miguel; Ferreira, Albano; Gonçalves, Mauer; Fortes, FilomenoThe scientific and technological evolution of contemporary medicine demands a new profile of professionals: up-to-date, ethical, multidisciplinary, and prepared to integrate biomedical knowledge with digital tools such as artificial intelligence (AI). NOVA University of Lisbon, Agostinho Neto University from Luanda and Katyavala Bwila University from Benguela have been adapting their educational programmes, pos...
The neglected contribution of streptomycin to the tuberculosis drug resistance ...
Rocha, Deisy M. G. C.; Viveiros, Miguel; Saraiva, Margarida; Osório, Nuno S.The airborne pathogen <i>Mycobacterium tuberculosis</i> is responsible for a present major public health problem worsened by the emergence of drug resistance. <i>M. tuberculosis</i> has acquired and developed streptomycin (STR) resistance mechanisms that have been maintained and transmitted in the population over the last decades. Indeed, STR resistant mutations are frequently identified across the main <i>M. t...
Whole-genome sequencing as a tool for studying the microevolution of drug-resis...
Diniz, Jaciara; von Groll, Andrea; Unis, Gisela; Dalla-Costa, Elis Regina; Rosa Rossetti, Maria Lúcia; Vianna, Júlia Silveira; Ramos, Daniela FernandesTreatment of drug-resistant tuberculosis requires extended use of more toxic and less effective drugs and may result in retreatment cases due to failure, abandonment or disease recurrence. It is therefore important to understand the evolutionary process of drug resistance in Mycobacterium tuberculosis. We here in describe the microevolution of drug resistance in serial isolates from six previously treated patie...
Genomic-based surveillance reveals high ongoing transmission of multi-drug-resi...
Salvato, Richard Steiner; Reis, Ana Júlia; Schiefelbein, Sun Hee; Gómez, Michael Andrés Abril; Salvato, Stéphanie Steiner; Silva, Larissa Vitória daGenomic-based surveillance on the occurrence of drug resistance and its transmission dynamics has emerged as a powerful tool for the control of tuberculosis (TB). A whole-genome sequencing approach, phenotypic testing and clinical-epidemiological investigation were used to undertake a retrospective population-based study on drug-resistant (DR)-TB in Rio Grande do Sul, the largest state in Southern Brazil. The a...
Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resist...
Gómez-González, Paula J.; Perdigão, João; Gomes, Pedro; Puyen, Zully M.; Santos-Lazaro, David; Napier, Gary; Hibberd, Martin L.; Viveiros, MiguelTuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the deadliest infectious diseases worldwide. Multidrug and extensively drug-resistant strains are making disease control difficult, and exhausting treatment options. New anti-TB drugs bedaquiline (BDQ), delamanid (DLM) and pretomanid (PTM) have been approved for the treatment of multi-drug resistant TB, but there is increasing resistance to them...
Large expert-curated database for benchmarking document similarity detection in...
Brown, Peter; Tan, Aik-Choon; El-Esawi, Mohamed A.; Liehr, Thomas; Blanck, Oliver; Gladue, Douglas P.; Almeida, Gabriel M. F.; Cernava, TomislavMade available in DSpace on 2020-12-11T01:57:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-10-29; Griffith University Gowonda HPC Cluster; Queensland Cyber Infrastructure Foundation; Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents tha...
Using genomics to understand the origin and dispersion of multidrug and extensi...
Perdigão, João; Gomes, Pedro; Miranda, Anabela; Maltez, Fernando; Machado, Diana; Silva, Carla; Phelan, Jody E.; Brum, Laura; Campino, SusanaPortugal is a low incidence country for tuberculosis (TB) disease. Now figuring among TB low incidence countries, it has since the 1990s reported multidrug resistant and extensively drug resistant (XDR) TB cases, driven predominantly by two strain-types: Lisboa3 and Q1. This study describes the largest characterization of the evolutionary trajectory of M/XDR-TB strains in Portugal, spanning a time-period of two...
Emergence of multidrug-resistant Mycobacterium tuberculosis of the Beijing line...
Perdigão, João; Silva, Carla; Maltez, Fernando; Machado, Diana; Miranda, Anabela; Couto, Isabel; Rabna, Paulo; Florez de Sessions, Paola; Phelan, JodyThe Beijing genotype comprises a highly disseminated strain type that is frequently associated with multidrug resistant (MDR) tuberculosis (TB) and increased transmissibility but, countries such as Portugal and Guinea-Bissau fall outside the regions phylogeographically associated with this specific genotype. Nevertheless, recent data shows that this genotype might be gradually emerging in these two countries as...
Laboratory services contribution to supporting public health and health service...
Vieira, Marisa Luísa; Rodrigues, Liliana; Almeida, Fernando; Fortes, Filomeno; de Sousa, Germano; Monteiro, Sandra; Silveira, Henrique; Viveiros, MiguelObjective: To promote the debate on the importance of the laboratory services in supporting public health and health services in Portuguese-speaking countries, from a global and One Health perspective. Methods: literature review, analysis of the preparatory papers for the 5th Tropical Medicine National Congress, presentations by speakers from Cape Verde, Angola and Portugal and the ensuing debate. Res...