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Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multic...

Pirnay, Jean-Paul; Djebara, Sarah; Steurs, Griet; Griselain, Johann; Cochez, Christel; De Soir, Steven; Glonti, Tea; Spiessens, An; Vanden Berghe, Emily

In contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced the expected results. Here we present the outcomes of a retrospective observational analysis of the first 100 consecutive cases of personalized BT of difficult-to-treat infections facilitated by a Belgian consortium i...


Antimicrobial storage and antibiotic knowledge in the community: a cross-sectio...

Cortez, Joana; Rosário, Edite; Pires, João E.; Taborda Lopes, João; Francisco, Moisés; Vlieghe, Erika; Brito, Miguel

Background - Antimicrobials are drugs that were once lifesavers and mainly curative. Nowadays their value is increasingly under pressure because of the fast and worldwide emergence of antimicrobial resistance, which, in low resources settings, frequently occurs in microorganisms that are likely to be transmitted in the community. Methods - A cross-sectional pilot study including 102 households within the 10th H...


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