9 documents found, page 1 of 1
Multifunctional graphene-based magnetic nanocarriers for combined hyperthermia ...
Rodrigues, Raquel Oliveira; Baldi, Giovanni; Doumett, Saer; Garcia-Hevia, Lorena; Gallo, Juan; Bañobre-López, Manuel; Dražić, GoranThe synthesis of hydrophilic graphene-based yolk-shell magnetic nanoparticles functionalized with copolymer pluronic F-127 (GYSMNP@PF127) is herein reported to achieve an efficient multifunctional biomedical system for mild hyperthermia and stimuli-responsive drug delivery. In vitro tests revealed the extraordinary ability of GYSMNP@PF127 to act as smart stimuli-responsive multifunctional nanomedicine platform fo...
A Tailor-made protocol to synthesize yolk-shell graphene-based magnetic nanopar...
Rodrigues, Raquel Oliveira; Baldi, Giovanni; Doumett, Saer; Gallo, Juan; Bañobre-López, Manuel; Dražić, Goran; Calhelha, Ricardo C.A simple tailor-made protocol to synthesize graphene-based magnetic nanoparticles (GbMNPs) for nanomedicine is herein reported. Different GbMNPs with very distinctive physicochemical and toxicological properties were synthesized by adjusting the number of carbon precursors in the coating of superparamagnetic iron oxide nanoparticles. In vitro tests show the ability to use these GbMNPs as intelligent and on-dema...
A tailor-made protocol to synthesize yolk-shell graphene-based magnetic nanopar...
Rodrigues, Raquel O.; Baldi, Giovanni; Doumett, Saer; Gallo, Juan; Bañobre-López, Manuel; Dražić, Goran; Calhelha, Ricardo C.; Ferreira, Isabel C. F. R.A simple tailor-made protocol to synthesize graphene-based magnetic nanoparticles (GbMNPs) for nanomedicine is herein reported. Different GbMNPs with very distinctive physicochemical and toxicological properties were synthesized by adjusting the number of carbon precursors in the coating of superparamagnetic iron oxide nanoparticles. In vitro tests show the ability to use these GbMNPs as intelligent and on-dema...
Multifunctional graphene-based magnetic nanocarriers for combined hyperthermia ...
Rodrigues, Raquel O.; Baldi, Giovanni; Doumett, Saer; Garcia-Hevia, Lorena; Gallo, Juan; Bañobre-López, Manuel; Dražić, Goran; Calhelha, Ricardo C.The synthesis of hydrophilic graphene-based yolk-shell magnetic nanoparticles functionalized with copolymer pluronic F-127 (GYSMNP@PF127) is herein reported to achieve an efficient multifunctional biomedical system for mild hyperthermia and stimuli-responsive drug delivery. In vitro tests revealed the extraordinary ability of GYSMNP@PF127 to act as smart stimuli-responsive multifunctional nanomedicine platform ...
Multifunctional graphene-based magnetic nanocarriers optimized with copolymer P...
Rodrigues, Raquel Oliveira; Baldi, Giovanni; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Silva, Adrián; Lima, Rui A.; Gomes, HelderThe limitations of current cancer therapies prompt the urgent need for a more effective therapeutic strategy [1]. Graphene-based magnetic nanoparticles (GbMNPs) due to their unique properties, such as high chemical and thermal stability, high charge carrier mobility, large surface area for functionalization and superparamagnetic properties, have the potentiality to be used as efficient multifunctional nanocarri...
Development of highly hydrophilic yolk-shell Fe3O4@C magnetic nanoparticles: a ...
Rodrigues, Raquel Oliveira; Doumett, Saer; Baldi, Giovanni; Bañobre-López, Manuel; Gallo, Juan; Lima, Rui A.; Silva, Adrián; Gomes, HelderDue to their remarkable physicochemical properties acquired at the nanoscale, magnetic nanoparticles (MNPs) are of interest in several disciplines, such as data storage, water purification, biochips and biomedicine (1). In order to prevent the oxidation of the MNPs, and their aggregation, several procedures have been developed to encapsulate them as a magnetic core (2). In particular, carboncoated nanoparticles...
Development of stimuli-responsive graphene-based yolk-shell magnetic nanopartic...
Rodrigues, Raquel Oliveira; Baldi, Giovanni; Doumett, Saer; Bañobre-López, Manuel; Gallo, Juan; Dražić, Goran; Lima, Rui A.; Silva, AdriánMagnetic drug delivery systems have attracted much attention in the last decades due to the possibility to improve the therapeutic efficacy of anticancer drugs, by enabling instable and poorly soluble drug agents to reach tumour cells after being guided by low magnetic fields and monitored by magnetic resonance imaging (MRI) [1]. Hence, a lower amount of anticancer drug is needed and the typical side effects of...
Antibacterial paper based on composite coatings of nanofibrillated cellulose an...
Martins, Natercia C. T.; Freire, Carmen S. R.; Neto, Carlos Pascoal; Silvestre, Armando J. D.; Causio, Jessica; Baldi, Giovanni; Sadocco, PatriziaNew composites of nanofibrillated cellulose (NFC) and ZnO nanoparticles (NP) have been prepared by electrostatic assembly in aqueous medium and using polyelectrolytes as macromolecular linkers. Selected NFC/ZnO systems were employed as fillers in starch based coating formulations for Eucalyptus globulus-based paper sheets. Using this method, antibacterial paper with low content of ZnO (<0.03%) and slight improv...
Electrostatic assembly of Ag nanoparticles onto nanofibrillated cellulose for a...
Martins, Natércia C. T.; Freire, Carmen S. R.; Pinto, Ricardo J. B.; Fernandes, Susana C. M.; Neto, Carlos Pascoal; Silvestre, Armando J. D.Nanofibrillated cellulose offers new technological solutions for the development of paper products. Here, composites of nanofibrillated cellulose (NFC) and Ag nanoparticles (NP) were prepared for the first time via the electrostatic assembly of Ag NP (aqueous colloids) onto NFC. Distinct polyelectrolytes have been investigated as macromolecular linkers in order to evaluate their effects on the building-up of Ag...