5 documents found, page 1 of 1
High frequency of psychosis in late-stage Parkinson’s disease
Chendo, Inês; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Sousa, Catarina Severiano; Coelho, Miguel; Voon, Valerie; Ferreira, Joaquim J.Background Psychosis is a frequent non-motor symptom in Parkinson’s disease (PD). Estimates of the frequency of Parkinsońs disease psychosis (PDP) vary widely. Knowledge about the frequency and phenomenology of psychosis in late-stage (LS) PD patients is limited. This study aimed to determine the frequency of psychosis in LSPD patients through clinical diagnostic interview (CDI) (gold standard), according to NI...
High frequency of psychosis in late-stage Parkinson's disease
Chendo, Inês; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Sousa, Catarina Severiano; Coelho, Miguel; Voon, Valerie; Ferreira, Joaquim J.Background: Psychosis is a frequent non-motor symptom in Parkinson’s disease (PD). Estimates of the frequency of Parkinsońs disease psychosis (PDP) vary widely. Knowledge about the frequency and phenomenology of psychosis in late-stage (LS) PD patients is limited. This study aimed to determine the frequency of psychosis in LSPD patients through clinical diagnostic interview (CDI) (gold standard), according to N...
EMOTICOM: A neuropsychological test battery to Evaluate Emotion, motivation, Im...
Bland, Amy R.; Roiser, Jonathan P.; Mehta, Mitul A.; Schei, Thea; Boland, Heather; Campbell-Meiklejohn, Daniel K.; Emsley, Richard A.; Munafo, Marcus R.In mental health practice, both pharmacological and non-pharmacological treatments are aimed at improving neuropsychological symptoms, including cognitive and emotional impairments. However, at present there is no established neuropsychological test battery that comprehensively covers multiple affective domains relevant in a range of disorders. Our objective was to generate a standardized test battery, comprise...
Imbalance in habitual versus goal directed neural systems during symptom provoc...
Banca, Paula; Voon, Valerie; Vestergaard, Martin D; Philipiak, Gregor; Almeida, Inês; Pocinho, Fernando; Relvas, João; Castelo-Branco, MiguelIntrusive thoughts and compulsive urges to perform stereotyped behaviours are typical symptoms of obsessive-compulsive disorder. Emerging evidence suggests a cognitive bias towards habit formation at the expense of goal-directed performance in obsessive-compulsive disorder. In this study, we test this hypothesis using a novel individualized ecologically valid symptom provocation design: a live provocation funct...
Increased ventral striatal volume in college-aged binge drinkers
Howell, Nicholas A.; Worbe, Yulia; Lange, Iris; Tait, Roger; Irvine, Michael; Banca, Paula; Harrison, Neil A; Bullmore, Edward T.; Hutchison, William D.Background: Binge drinking is a serious public health issue associated with cognitive, physiological, and anatomical differences from healthy individuals. No studies, however, have reported subcortical grey matter differences in this population. To address this, we compared the grey matter volumes of college-age binge drinkers and healthy controls, focusing on the ventral striatum, hippocampus and amygdala. Met...