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Blood-borne virus testing in European emergency departments: current evidence a...

Smout, E; Ruf, M; Buti, M; Pinto, IV; Nebbia, G; Hunter, L; Aldersley, MA; Esteves, C; Medina, D; Llaneras, J; Douthwaite, S; Page, EE

Innovative testing approaches are needed to meet global targets for the blood-borne viruses (BBVs) HIV, hepatitis B virus (HBV) and hepatitis C virus (HCV). We conducted a systematic review of BBV testing in emergency departments (EDs) in Europe to evaluate prevalence, effectiveness of ED testing and linkage to care (LTC). We searched PubMed, Embase and Cochrane Library for articles on ED BBV testing published ...

Date: 2025   |   Origin: Hospital de Cascais

Emergency department contribution to HCV elimination in the Iberian Peninsula

Buti, M; Vaz-Pinto, I; Magno Pereira, V; Casado, M; Llaneras, J; Barreira, A; Esteves, C; Guimarães, M; Gorgulho, A; Mourão, T; Xavier, E; Jasmins, L

Background: Undiagnosed cases of hepatitis C virus (HCV) infection result in significant morbidity and mortality, further transmission, and increased public health costs. Testing in emergency departments (EDs) is an opportunity to expand HCV screening. The goal of this project was to increase the proportion of eligible patients screened for HCV in urban areas. Methods: An opportunistic automated HCV screening p...

Date: 2024   |   Origin: Hospital de Cascais

Simultaneous determination of melatonin and trans-resveratrol in wine by disper...

Viegas, Olga; Esteves, C; Rocha, J; Melo, A; Ferreira, IMPLVO

The discovery of melatonin (Mel) in wines triggered a new interest in the paradigm of health benefits and wine consumption, usually ascribed to trans-resveratrol (trans-RSV). In this context, a dispersive liquid-liquid microextraction for the analysis of Mel and trans-RSV in wines by LC-FLD was developed. A 2(6-1) factorial design was used to identify the significant variables (p < 0.05) and Central Composite D...


Avascular femoral necrosis as part of Cushing syndrome presentation: a case report

Salazar, D; Esteves, C; Ferreira, MJ; Pedro, J; Pimenta, T; Portugal, R; Carvalho, D

Background: The clinical characteristics and complications of Cushing syndrome (CS) are well known and described in the literature. Nevertheless, rare, atypical presentations may go unnoticed. Osteonecrosis is a well-documented complication of glucocorticoid therapy. However, endogenous hypercortisolism is a rare, but relevant, cause of bone avascular necrosis. We describe the case of a woman with CS undiagnose...


Correction to: Avascular femoral necrosis as part of Cushing syndrome presentat...

Salazar, D; Esteves, C; Ferreira, MJ; Pedro, J; Pimenta, T; Portugal, R; Carvalho, D


Cushing's syndrome: Consequences of late diagnosis after bariatric surgery

Pedro, J; Belo, S; Guerreiro, V; Ferreira, MJ; Salazar, D; Costa, C; Esteves, C; Pereira, J; Freitas, P; Carvalho, D

Prior to bariatric surgery, endocrine causes of obesity must be excluded. The diagnosis of osteoporosis in a male requires the study of secondary causes of this condition. The diagnostic delay of Cushing's syndrome may have irreversible consequences.


Assessing the Effects of the Transition from Multiple Daily Insulin Injections ...

Oliveira, SC; Neves, C; Esteves, C; Neves, JS; Oliveira, AI; Pereira, M; Arteiro, Cristina; Costa, A; Redondo, MD; Baltazar, R; Carvalho, Davide

Introduction: Intensive insulin therapy is currently the main treatment in type I diabetes mellitus (DM) which includes multiple daily insulin injections (MDI) and continuous subcutaneous insulin infusion (CSII). The latter has become the preferred therapeutic mode, since it better mimics the physiological pancreatic action, althought there is limited evidence that supports its superiority to MDI. The aim of ou...


A challenging coexistence of central diabetes insipidus and cerebral salt wasti...

Costa, MM; Esteves, C; Castedo, J; Pereira, J; Carvalho, D

Background: Combined central diabetes insipidus and cerebral salt wasting syndrome is a rare clinical finding. However, when this happens, mortality is high due to delayed diagnosis and/or inadequate treatment. Case presentation: A 42-year-old white man was referred to neurosurgery due to a non-functional pituitary macroadenoma. He underwent a partial resection of the tumor on July 2, 2015. On the day following...


Severe hypoglycaemia in diabetic patients in Pre-hospital and Emergency Departm...

Esteves, C; Neves, C; Sá, J; Carvalho, D

Objective: We aimed to characterize hypoglycaemia episodes and patients examined by a Pre-hospital Medical Emergency Unit (PH) and in the Emergency Department (ED) of our hospital. Results: We identified 86 episodes of severe hypoglycaemia (PH: n 37; ED: n 49; both: n 12). Hypoglycaemia accounted for 4.7% of all emergency calls attended by the PH (n 793) and 0.11% of all ED episodes (n 54,366). Among episodes e...


Effects of bariatric surgery on blood pressure of non-hypertensive obese patients

Neves, J. S; Castro-Oliveira, Sofia; Souteiro, P; Bettencourt-Silva, R; Magalhães, D; Costa, M. M; Saavedra, A; Oliveira, J; Cunha, F; Lau, E


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