23 documents found, page 1 of 3
A meta-analysis of epigenome-wide association studies of ultra-processed food c...
Llauradó-Pont, J; Stratakis, N; Fiorito, G; Handakas, E; Neumann, A; Barros, H; Brantsæter, AL; Chang, K; Chatzi, L; Felix, JF; Grazuleviciene, R"Background/objective: There is limited knowledge on how diet affects the epigenome of children. Ultra-processed food (UPF) consumption is emerging as an important factor impacting health, but mechanisms need to be uncovered. We therefore aimed to assess the association between UPF consumption and DNA methylation in children. Methods: We conducted a meta-analysis of epigenome-wide association studies (EWAS) fro...
Urban environment during pregnancy and lung function, wheezing, and asthma in s...
Abellan, A; Warembourg, C; Mensink-Bout, SM; Ambros, A; de Castro, M; Fossati, S; Guxens, M; Jaddoe, VW; Nieuwenhuijsen, MJ; Vrijheid, M; Santos, SThe urban environment during pregnancy may influence child's respiratory health, but scarce evidence exists on systematic evaluation of multiple urban exposures (e.g., air pollution, natural spaces, noise, built environment) on children's lung function, wheezing, and asthma development. We aimed to examine the association of the urban environment during pregnancy with lung function, preschool wheezing, and scho...
Green spaces and respiratory, cardiometabolic, and neurodevelopmental outcomes:...
Fernandes, A; Avraam, D; Cadman, T; Dadvand, P; Guxens, M; Binter, A-C; Pinot de Moira, A; Nieuwenhuijsen, M; Duijts, L; Julvez, J; De Castro, MStudies evaluating the benefits and risks of green spaces on children's health are scarce. The present study aimed to examine the associations between exposure to green spaces during pregnancy and early childhood with respiratory, cardiometabolic, and neurodevelopmental outcomes in school-age children. We performed an Individual-Participant Data (IPD) meta-analysis involving 35,000 children from ten European bi...
Prenatal Urban Environment and Blood Pressure Trajectories From Childhood to Ea...
Gonçalves Soares, A; Santos, S; Seyve, E; Nedelec, R; Puhakka, S; Eloranta, A-M; Mikkonen, S; Yuan, WL; Lawlor, DA; Heron, J; Vrijheid, M; Lepeule, JBackground: Prenatal urban environmental exposures have been associated with blood pressure in children. The dynamic of these associations across childhood and later ages is unknown. Objectives: The purpose of this study was to assess associations of prenatal urban environmental exposures with blood pressure trajectories from childhood to early adulthood. Methods: Repeated measures of systolic blood pressure (S...
Ambient air temperature exposure and foetal size and growth in three European b...
Essers, E; Granés, L; Delaney, S; Ballester, J; Santos, S; Petricola, S; Yang, TC; Fernández-Somoano, A; Bereziartua, A; Ballester, F; Tardón, AIntroduction: Ambient air temperature may affect birth outcomes adversely, but little is known about their impact on foetal growth throughout pregnancy. We evaluated the association between temperature exposure during pregnancy and foetal size and growth in three European birth cohorts. Methods: We studied 23,408 pregnant women from the English Born in Bradford cohort, Dutch Generation R Study, and Spanish INMA...
Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysi...
Robinson, L; Roccaldo, R; Rodrigues, D; Rodriguez Perez, MdC; Rodríguez Villamizar, LA; Rodríguez, AY; Roggenbuck, U; Rohloff, P; Rohner, FBackground: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods: We used data from 3663 population-based studies with 222 million participants that...
Gestational age at birth and body size from infancy through adolescence: An ind...
Vinther, JL; Cadman, T; Avraam, D; Ekstrom, CT; Sorensen, TIA; Elhakeem, A; Santos, AC; de Moira, AP; Heude, B; Iñiguez, C; Pizzi, C; Simons, EBackground Preterm birth is the leading cause of perinatal morbidity and mortality and is associated with adverse developmental and long-term health outcomes, including several cardiometabolic risk factors and outcomes. However, evidence about the association of preterm birth with later body size derives mainly from studies using birth weight as a proxy of prematurity rather than an actual length of gestation. ...
Associations of green and blue space exposure in pregnancy with epigenetic gest...
Marques, I; Santos, S; Monasso, GS; Fossati, S; Vrijheid, M; Nieuwenhuijsen, M; Jaddoe, VWV; Felix, JFEarly life is seen as a particularly sensitive period for environmental exposures. Natural space exposure during pregnancy has been associated with offspring health. Epigenetic gestational age acceleration, a discrepancy between clinical and DNA methylation-based gestational age, may underlie these associations. In 1359 mother-newborn pairs from the population-based Generation R Study, we examined the associati...
Exposure to natural environments during pregnancy and birth outcomes in 11 euro...
Torres Toda, M; Avraam, D; James Cadman, T; Fossati, S; de Castro, M; Dedele, A; Donovan, G; Elhakeem, A; Estarlich, M; Fernandes, A; Gonçalves, RResearch suggests that maternal exposure to natural environments (i.e., green and blue spaces) promotes healthy fetal growth. However, the available evidence is heterogeneous across regions, with very few studies on the effects of blue spaces. This study evaluated associations between maternal exposure to natural environments and birth outcomes in 11 birth cohorts across nine European countries. This study, par...
Height and body-mass index trajectories of school-aged children and adolescents...
Horimoto, AR; Hormiga, CM; Horta, BL; Houti, L; Howitt, C; Htay, TT; Htet, AS; Htike, MMT; Hu, Y; Huerta, JM; Huhtaniemi, IT; Huidumac Petrescu, CBackground: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods: For this pooled analysis, we used a database of cardiometabolic risk factors colla...