11 documents found, page 1 of 2

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Metabolism-targeted therapy in NSCLC – A new theranostics inhalation approach u...

Mendes, Cindy; Martins, Filipa; Granja, Sara; Gonçalves, Joana; Barros, Hélio; Casimiro, Teresa; Aguiar-Ricardo, Ana; Silva, Fernanda; Abreu, Bruna

Funding Information: The institutions are funded by Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNO-VA4Health (UIDB/04462/2020 and UIDP/04462/2020), to MOSTMICRO-ITQB (UIDB/04612/2020 and UIDP/04612/2020) and the Associated Laboratory LS4FUTURE (LA/P/0087/2020). During the course of PhD, Cindy Mendes was funded by Lig...


H2S-Synthesizing Enzymes Are Putative Determinants in Lung Cancer Management to...

Hipólito, Ana; Mendes, Cindy; Martins, Filipa; Lemos, Isabel; Francisco, Inês; Cunha, Fernando; Almodôvar, Teresa; Albuquerque, Cristina

Funding Information: The institutions are funded by Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/2020), MOSTMICRO-ITQB (UIDB/04612/2020 and UIDP/04612/2020), and the Associated Laboratory LS4FUTURE (LA/P/0087/2020). The study was partially supported by a Merck KGaA, Darmstad...


Metabolic profiling and combined therapeutic strategies unveil the cytotoxic po...

Mendes, Cindy; Lemos, Isabel; Hipólito, Ana; Abreu, Bruna; Freitas-Dias, Catarina; Martins, Filipa; Pires, Rita F.; Barros, Hélio; Bonifácio, Vasco D.B.

Funding Information: The institutions are funded by Fundac\u00B8 \u00E3o para a Ci\u00EAncia e a Tecnologia/Minist\u00E9rio da Ci\u00EAncia, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNO-VA4Health [grant numbers UIDB/04462/2020 and UIDP/04462/2020], to MOSTMICRO-ITQB [grant numbers UIDB/04612/2020 and UIDP/04612/2020] and the Associated Laboratory LS4FUTURE [grant number LA/P/...


NSCLC presents metabolic heterogeneity, and there is still some leeway for EGF ...

Mendes, Cindy; Lemos, Isabel; Francisco, Inês; Almodôvar, Teresa; Cunha, Fernando; Albuquerque, Cristina; Gonçalves, Luís G.; Serpa, Jacinta

Funding Information: The institutions are funded by Fundação para a Ciência e Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/2020), to MOSTMICRO-ITQB (UIDB/04612/2020 and UIDP/04612/2020) and the Associated Laboratory LS4FUTURE (LA/P/0087/2020). Cindy Mendes was funded by a FCT individual Ph.D. fellowshi...


Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by ...

Nunes, Sofia C.; Ramos, Cristiano; Santos, Inês; Mendes, Cindy; Silva, Fernanda; Vicente, João B.; SA, Pereira; Félix, Ana; Gonçalves, Luís G.

Funding Information: Funding. This research was supported by Funda??o para a Ci?ncia e Tecnologia (FCT) (Ph.D. ProRegeM program, Ref: PD/BD/105893/2014; FCT individual Ph.D. fellowship Ref: 2020.06956.BD) and iNOVA4 Health (Project 4 and Project 21). iNOVA4Health-UID/Multi/04462/2013 is a program financially supported by Funda??o para a Ci?ncia e Tecnologia/ Minist?rio da Educa??o e Ci?ncia, through national fu...


The Activation of Endothelial Cells Relies on a Ferroptosis-Like Mechanism

Lopes-Coelho, Filipa; Martins, Filipa; Hipólito, Ana; Mendes, Cindy; Sequeira, Catarina O.; Pires, Rita F.; Almeida, António M.; Bonifácio, Vasco D.B.

Funding: The project was funded by IPOLFG EPE and by iNOVA4Health (UID/Multi/04462/2019) a program financially supported by Fundação para a Ciência e Tecnologia (FCT)/Ministério da Educação e Ciência, through national funds. We also acknowledge funding from FCT-MCTES through the project DREAM—PTDC/MEC-ONC/29327/2017. FL-C PhD fellowship was funded by FCT (PD/BD/128337/2017).; The activation of endothelial cells...


Molecular and Metabolic Reprogramming

Hipólito, Ana; Martins, Filipa; Mendes, Cindy; Lopes-Coelho, Filipa; Serpa, Jacinta

Funding: The research group was funded by IPOLFG EPE and by iNOVA4Health (UID/Multi/04462/2019) a program financially supported by Fundação para a Ciência e Tecnologia (FCT)/ Ministério da Educação e Ciência, through national funds. All the fellowships were funded by FCT: AH (SFRH/BD/148441/ 2019), FM (2020.04780.BD), CM (2020.06956.BD), FL-C (PD/ BD/128337/2017).; Metastasis is a major hurdle to the efficient ...


Polyurea Dendrimer Folate-Targeted Nanodelivery of l-Buthionine sulfoximine as ...

Cruz, Adriana; Mota, Pedro; Ramos, Cristiano; Pires, Rita F; Mendes, Cindy; Silva, José P; Nunes, Sofia C; Bonifácio, Vasco D B; Serpa, Jacinta

The research was funded by iNOVA4Health—UID/Multi/04462/, a program financially supported by the Fundação para a Ciência e a Tecnologia—Ministério da Educação e Ciência (FCT-MCTES), through nationalfunds and co-funded by FEDER under the PT2020 Partnership Agreement. We also acknowledge funding from FCT-MCTES through the project DREAM—PTDC/MEC-ONC/29327/2017 and FAI2017 from IPOLFG internal funding.; : Ovarian c...


Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment ...

Santos, Inês; Ramos, Cristiano; Mendes, Cindy; Sequeira, Catarina O.; Tomé, Catarina S.; Fernandes, Dalila G.H.; Mota, Pedro; Pires, Rita F.

The research was funded by iNOVA4Health UID/Multi/04462, a program financially supported by Fundação para a Ciência e Tecnologia/Ministério da Educação e Ciência (FCT-MCTES), through national funds, and co-funded by FEDER under the PT2020 Partnership Agreement. We also acknowledge funding from FCT-MCTES through project DREAM PTDC/MEC-ONC/29327/2017.; Ovarian cancer is the main cause of death from gynecological ...


Metabolic Remodelling

Mendes, Cindy; Serpa, Jacinta

The research was funded by iNOVA4Health—UID/Multi/04462, a program financially supported by Fundação para a Ciência e Tecnologia/Ministério da Educação e Ciência (FCT-MCTES), through national funds and co-funded by FEDER under the PT2020 Partnership Agreement.; Metabolic remodelling is a hallmark of cancer, however little has been unravelled in its role in chemoresistance, which is a major hurdle to cancer cont...


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