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Poor immune reconstitution in HIV-infected patients associates with high percen...
Horta, Ana; Nóbrega, Cláudia; Machado, Pedro Amorim; Teixeira, Vítor Emanuel Coutinho; Silva, Palmira Conceição Araújo Barreira; Boavida, SusanaCD4(+) regulatory T cells (Tregs) are essential for the maintenance of the immune system's equilibrium, by dampening the activation of potential auto-reactive T cells and avoiding excessive immune activation. To correctly perform their function, Tregs must be maintained at the right proportion with respect to effector T cells. Since this equilibrium is frequently disrupted in individuals infected with the human...
A case control study on the diagnostic potential of multiantigen serological te...
Duarte, Raquel; Afonso, Andrea; Ferreira, Carina; Roque, Susana; Vasconcelos, Olga; Castro, Rui Sarmento; Tavares, Margarida; Caldas, CátiaBackground: Eradicating tuberculosis (TB) in European countries with high incidence, such as Portugal, rely to a great extent on the ability to perform early accurate diagnosis. For the first time, the diagnostic value of two serologic tests, TB STAT-PAK II and MAPIA, was evaluated for rapid tuberculosis detection in a Portuguese cohort. Materials and Methods: A multicentre case-control study was performed on i...