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Cyclotriphosphazene-based derivatives for antibacterial Applications: an update...

Su, Xiqi; Wang, Le; Xie, JingHua; Liu, XiaoHui; Tomás, Helena

As a phosphorus scaffold, hexachlorocyclotriphosphazene (HCCP) is widely used for the synthesis of varieties of derivatives, including metal-binding complexes and several unique organometallic compounds, which exhibit potential catalytic, flame retardant and bio logical activities. Some metal-binding HCCP derivatives have shown antibacterial activities as free ligands and metal complexes. These derivatives can ...


Morpholino-functionalized phosphorus dendrimers for precision regenerative medi...

Li, Aijun; Fan, Yu; Cao, Xueyan; Chen, Liang; Wang, Le; Alves, Carla S.; Mignani, Serge; Majoral, Jean Pierre; Tomás, Helena; Shi, Xiangyang

A novel bioactive macromolecule based on morpholino-functiona lized phosphorus dendrimers (generation 2, G2-Mor+ ) was devel oped for osteogenic differentiation of mesenchymal stem cells (MSCs). Interestingly, through in vitro tests, it was shown that G2- Mor+ dendrimer can strongly promote the transformation of MSCs into osteoblasts, which implies the potential application of phos phorus de medicine.


A simple and sensitive method for determination of Norfloxacin in pharmaceutica...

Ye, Zhuo; Wang, Le; Wen, Jianguo

;Propos-se, por essa abordagem, novo método voltamétrico, com alta sensibilidade e faixa linear de detecção mais ampla, para a determinação de norfloxacino. O sensor voltamétrico utilizado foi fabricado simplismente por cobertura de camada de óxido de grafeno (GO) e filme de Nafion em eletrodo de cabrono vítreo. A vantagem do método proposto foi a resposta eletroquímica sensível para o norfloxacino, atribuída à...

Date: 2015   |   Origin: Oasisbr

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