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Iodine supplementation: compliance and association with adverse obstetric and n...

Objectives: Over 1.9 billion people worldwide are living in areas estimated to be iodine insufficient. Strategies for iodine supplementation include campaigns targeting vulnerable groups, such as women in pre-conception, pregnancy and lactation. Portuguese women of childbearing age and pregnant women were shown to be mildly-to-moderately iodine deficient. As a response, in 2013, the National Health Authority (N...

Deoxynivalenol exposure assessment through a modelling approach of food intake ...

Deoxynivalenol (DON), an enteropathogenic mycotoxin produced by Fusarium species, is usually associated with adverse health outcomes such as gastrointestinal diseases and immunotoxicity. To estimate DON exposure of the Portuguese population at national level, a modelling approach, based on data from 94 Portuguese volunteers, was developed considering the inputs of the food consumption data generated within the ...

Dietary exposure to aflatoxins in the Portuguese population – the use of biomon...

Background: Human biomonitoring (HBM) is an important tool to assess the human exposure to chemicals, contributing to describe trends of exposure over time and to identify population groups that could be under risk. Aflatoxins (AFTs) are genotoxic and carcinogenic compounds causing hepatocellular carcinoma (HCC), the third leading cause of cancer deaths worldwide. In Portugal, scarce data are available regardin...

Deoxynivalenol exposure assessment through a modelling approach of food intake ...

Deoxynivalenol (DON), an enteropathogenic mycotoxin produced by Fusarium species, is usually associated with adverse health outcomes such as gastrointestinal diseases and immunotoxicity. To estimate DON exposure of the Portuguese population at national level, a modelling approach, based on data from 94 Portuguese volunteers, was developed considering the inputs of the food consumption data generated within the ...

Impact of iodine supplementation during preconception, pregnancy and lactation ...

Background: Iodine deficiency is the most common cause of preventable brain harm and cognitive impairment in children. Portuguese women of childbearing age, pregnant women and their progeny were shown to have inadequate iodine intake. Consequently, the Portuguese Health Authorities have recommended a daily supplementation with 150-200 µg iodine in preconception, pregnancy, and lactation. The IodineMinho study i...

Food Consumption Data as a Tool to Estimate Exposure to Mycoestrogens

Zearalenone and alternariol are mycotoxins produced by Fusarium and Alternaria species, respectively, that present estrogenic activity and consequently are classified as endocrine disruptors. To estimate the exposure of the Portuguese population to these two mycotoxins at a national level, a modelling approach, based on data from 94 Portuguese volunteers, was developed considering as inputs: i) the food consump...

Exposição da população portuguesa a micotoxinas: o contributo da biomonitorizaç...

As micotoxinas constituem um grupo de contaminantes alimentares que poderão provocar vários efeitos tóxicos na saúde humana, entre eles efeitos estrogénicos, imunotóxicos, nefrotóxicos e teratogénicos. É por isso importante avaliar a exposição humana a estes compostos, através da análise direta dos seus biomarcadores em amostras biológicas. Em Portugal existem poucos dados disponíveis de exposição a micotoxinas...

Definition of immunological nonresponse to antiretroviral therapy: a systematic...

Terms and criteria to classify people living with HIV on antiretroviral therapy who fail to achieve satisfactory CD4 T-cell counts are heterogeneous, and need revision and summarization. Background: Terms and criteria to classify people living with HIV on antiretroviral therapy who fail to achieve satisfactory CD4+ T-cell counts are heterogeneous, and need revision and summarization. Methods: We performed a sys...

Unraveling the prevalence of zearalenone biomarkers of exposure in the Portugue...

Zearalenone (ZEN) is a mycotoxin that occurs widely in food commodities with particular incidence in cereals. Due to chemical structures similar to the endogenous estrogen 17-β-estradiol, ZEN and its metabolites exert estrogenic toxicity. Therefore, it is crucial to assess ZEN exposure among the population. Biomarker-driven research appeared as a promising method to assess the mycotoxin exposure in humans. For ...

Food handlersknowledge about food allergy - A study in restaurants and food uni...