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Global impact of fixed-dose combination therapies on cardiovascular mortality a...

Watkins, David A.; Pickersgill, Sarah; Flood, David; Gaziano, Thomas A.; Huffman, Mark D.; Islam, Shofiqul; Joseph, Philip; Perel, Pablo

Background: Uptake of drugs for primary and secondary prevention of cardiovascular disease is low in many countries. Single-pill combination (SPC) therapies consisting of a statin and 1 or more antihypertensive drugs, with or without aspirin, can reduce rates of fatal and nonfatal cardiovascular disease, but their use is currently limited. Objectives: The authors modeled the potential impact of widespread adopt...

Date: 2025   |   Origin: Repositório da Universidade de Lisboa
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