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The Porto European Cancer Research Summit 2021

Ringborg, U; Berns, A; Celis, JE; Heitor, M; Tabernero, J; Schüz, J; Baumann, M; Henrique, R; Aapro, M; Basu, P; Beets-Tan, R; Besse, B; Cardoso, F

Key stakeholders from the cancer research continuum met in May 2021 at the European Cancer Research Summit in Porto to discuss priorities and specific action points required for the successful implementation of the European Cancer Mission and Europe's Beating Cancer Plan (EBCP). Speakers presented a unified view about the need to establish high-quality, networked infrastructures to decrease cancer incidence, in...


Global, regional, and national age-sex-specific mortality for 282 causes of dea...

Roth, GA; Abate, D; Abate, KH; Abay, SM; Abbafati, C; Abbasi, N; Abbastabar, H; Abd-Allah, L; Abdela, J; Abdelalim, A; Abdollahpour, I; Abdulkader, RS

Background Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly availa...


Genetic variants in the IL1A gene region contribute to intestinal-type gastric ...

Durães, C; Muñoz, X; Bonet, C; García, N; Venceslá, A; Carneiro, F; Peleteiro, B; Lunet, N; Barros, H; Lindkvist, B; Boutron-Ruault, M-C

The most studied genetic susceptibility factors involved in gastric carcinoma (GC) risk are polymorphisms in the inflammation-linked genes interleukin 1 (IL1) B and IL1RN. Despite the evidence pointing to the IL1 region, definite functional variants reproducible across populations of different genetic background have not been discovered so far. A high density linkage disequilibrium (LD) map of the IL1 gene clus...


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