Studies analyzing the relationship between BK polyomavirus (BKV) or JC polyomavirus (JCV) infection and kidney transplant (KT) long term clinical outcomes are scarce. Therefore, we evaluated this relationship in a single-center retrospective cohort of 288 KT patients followed for 45.4(27.5; 62.5) months. Detection of BKV viremia in two consecutive analyses led to discontinuation of antimetabolite and initiation...
Kidney transplant (KT) recipients have an increased risk for urothelial carcinoma. A role for JC virus (JCV) in human cancers is not yet proved but there is an increasingly reported association between BK virus (BKV) nephropathy and renourinary neoplasms. We report a KT recipient who developed a high-grade urothelial carcinoma 5 years after a diagnosis of JCV nephropathy and 9 years after kidney transplantation...
The incidence of end-stage renal disease (ESRD) is increasing worldwide. When compared to dialysis, renal transplantation (RT) leads to a survival advantage and to an improvement in quality of life in most ESRD patients. Additionally, from a societal perspective, RT is the most cost-effective modality of renal replacement therapy (RRT) for eligible patients. In the last decades, RT has prolonged and improved th...
A doença renal crónica (DRC) é um importante problema de saúde pública com elevado impacto nos doentes afetados por esta patologia. A DRC é um grande multiplicador de risco em doentes com diabetes, hipertensão, doença cardíaca e acidente vascular cerebral. A desnutrição é uma complicação prevalente nos doentes em hemodiálise (HD) e apresenta uma elevada correlação com a mortalidade e morbilidade. A albumina é u...