3 documents found, page 1 of 1
Molecular cytogenetic pilot study on pleomorphic adenomas of salivary glands
Thielker, Jovanna; Weise, Anja; Othman, Moneeb A. K.; Carreira, Isabel M.; Melo, Joana B.; Von Eggeling, Ferdinand; Guntinas-Lichius, OrlandoPleomorphic adenomas (PAs) of salivary glands are the most frequent entity of solid parotid tumors. Nonetheless, their genetics is not yet well understood. Thus, the current study characterized 14 PAs using a unique combination of cytogenetic, molecular cytogenetic and/or molecular karyotyping based approaches. The current study applied G-banding based on trypsin treatment and Giemsa-staining in peripheral bloo...
Chromosomes in a genome-wise order: evidence for metaphase architecture
Weise, Anja; Bhatt, Samarth; Piaszinski, Katja; Kosyakova, Nadezda; Fan, Xiaobo; Altendorf-Hofmann, Annelore; Tanomtong, Alongklod; Chaveerach, ArunratJena University Hospital. Institute of Human Genetics. Jena, Germany.; Jena University Hospital. Institute of Human Genetics. Jena, Germany.; Jena University Hospital. Institute of Human Genetics. Jena, Germany.; Jena University Hospital. Institute of Human Genetics. Jena, Germany.; Jena University Hospital. Institute of Human Genetics. Jena, Germany.; Jena University Hospital. Department of General, Visceral u...
Molecular cytogenetic characterisation of a mosaic add(12)(p13.3) with an inv d...
Carreira, Isabel M.; Melo, Joana B.; Rodrigues, Carlos F. D.; Backx, Liesbeth; Vermeesch, Joris; Weise, Anja; Kosyakova, Nadezda; Oliveira, GuiomarBackground: Inverted duplications (inv dup) of a terminal chromosome region are a particular subset of rearrangements that often results in partial tetrasomy or partial trisomy when accompanied by a deleted chromosome. Associated mosaicism could be the consequence of a post-zygotic event or could result from the correction of a trisomic conception. Tetrasomies of distal segments of the chromosome 3q are rare ge...