2 documents found, page 1 of 1
Tuneable cellulose nanocrystal and tropoelastin-laden hyaluronic acid hydrogels
Silva, Cristiana R.; Babo, Pedro Miguel Sousa; Mithieux, Suzanne; Domingues, Rui Miguel Andrade; Reis, R. L.; Gomes, Manuela E.; Weiss, AnthonyHyaluronic acid (HA)-based hydrogels have been widely used as cell culture substrates, adhesives and fillers for clinical therapeutics, and drug delivery vehicles, with promising results. Due to the limited mechanical properties, degradation rates, and biological activity of HA, it is important that HA be chemically modified, cross-linked or reinforced with specific components to confer a versatile range of vis...
Injectable and magnetic responsive hydrogels with bioinspired ordered structures
Araújo-Custódio, Sandra; Gomez-Florit, Manuel; Tomás, Ana R.; Mendes, Bárbara B.; Babo, Pedro Miguel Sousa; Mithieux, Suzanne M; Weiss, AnthonyInjectable hydrogels are particularly interesting for applications in minimally invasive tissue engineering and regenerative medicine strategies. However, the typical isotropic microstructure of these biomaterials limits their potential for the regeneration of ordered tissues. In the present work, we decorated rod-shaped cellulose nanocrystals with magnetic nanoparticles and coated these with polydopamine and p...