2 documents found, page 1 of 1
Engineering magnetically responsive tropoelastin spongy-like hydrogels for soft...
Pesqueira, Tamagno; Almeida, Raquel Carvalho Ferreira Costa; Mithieux, Suzanne M.; Babo, Pedro Miguel Sousa; Franco, Albina Ribeiro; Mendes, Bárbara B.Magnetic biomaterials are a key focus in medical research. Tropoelastin is the soluble precursor of elastin and is a critical component of tissues requiring elasticity as part of their physiological function. By utilising the versatility of tropoelastin and the ability to tailor its properties, we developed a novel magnetic spongy-like hydrogel based on tropoelastin doped with magnetic properties by in situ pre...
Magnetically responsive tropoelastin hydrogel as a platform for soft tissue reg...
Pesqueira, Tamagno; Almeida, Raquel Costa; Mithieux, Suzanne M.; Reis, R. L.; Gomes, Manuela E.; Weiss, Anthony S.The natural polymer tropoelastin is a structural protein of ECM of tissues requiring elasticity as part of their function, including ligaments and tendons. Tropoelastin has an innate capacity of self-assembly into high-order structures, and together with elastic resilience, structural stability and bioactivity bring forth pleasant singularities in adopting it as a building block to fabricate hydrogels. Moreover...