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Circulating MicroRNA Expression Profiles in Patients with Stable and Unstable A...

Liu, Sudong; Guo, Xuemin; Zhong, Wei; Weng, Ruiqiang; Liu, Jing; Gu, Xiaodong; Zhong, Zhixiong

OBJECTIVES: High incidence and case fatality of unstable angina (UA) is, to a large extent, a consequence of the lack of highly sensitive and specific non-invasive markers. Circulating microRNAs (miRNAs) have been widely recommended as potential biomarkers for numerous diseases. In the present study, we characterized distinctive miRNA expression profiles in patients with stable angina (SA), UA, and normal coron...

Date: 2020   |   Origin: Oasisbr

Circulating Exosomal microRNAs as Biomarkers of Systemic Lupus Erythematosus

Li, Wengen; Liu, Sudong; Chen, Yongyu; Weng, Ruiqiang; Zhang, Ke; He, Xuechun; He, Chunmei

OBJECTIVES: Many studies indicate that microRNAs (miRNAs) could be potential biomarkers for various diseases. The purpose of this study was to investigate the clinical value of serum exosomal miRNAs in systemic lupus erythematosus (SLE). METHODS: Serum exosomes were isolated from 38 patients with SLE and 18 healthy controls (HCs). The expression of miR-21, miR-146a and miR-155 within exosomes was examined by re...

Date: 2020   |   Origin: Oasisbr

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