3 documents found, page 1 of 1
Revisiting IgG antibody reactivity to epstein-barr virus in myalgic encephalomy...
Sepúlveda, Nuno; Malato, João; Sotzny, Franziska; Grabowska, Anna D.; Fonseca, André; Cordeiro, Clara; Graça, Luís; Biecek, Przemyslaw; Behrends, UtaInfections by the Epstein-Barr virus (EBV) are often at the disease onset of patients suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). However, serological analyses of these infections remain inconclusive when comparing patients with healthy controls (HCs). In particular, it is unclear if certain EBV-derived antigens eliciting antibody responses have a biomarker potential for disease ...
Herpesviruses serology distinguishes different subgroups of patients from the U...
Domingues, Tiago Dias; Grabowska, Anna D.; Lee, Ji-Sook; Ameijeiras-Alonso, Jose; Westermeier, Francisco; Scheibenbogen, Carmen; Cliff, Jacqueline M.The evidence of an association between Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and chronic herpesviruses infections remains inconclusive. Two reasons for the lack of consistent evidence are the large heterogeneity of the patients’ population with different disease triggers and the use of arbitrary cutoffs for defining seropositivity. In this work we re-analyzed previously published serologic...
The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in myalgic encep...
Malato, João; Sotzny, Franziska; Bauer, Sandra; Freitag, Helma; Fonseca, André; Grabowska, Anna D.; Graça, Luís; Cordeiro, Clara; Nacul, LuísPeople with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) often report a high frequency of viral infections and flu-like symptoms during their disease course. Given that this reporting agrees with different immunological abnormalities and altered gene expression profiles observed in the disease, we aimed at answering whether the expression of the human angiotensin-converting enzyme 2 (ACE2), the m...