Played from a first-person perspective and centred around a mysterious device that creates portals, Portal (2007) and Portal 2 (2011), developed by Valve Corporation, are still regarded as some of the best titles ever produced. Their widespread success has also reached academia, inspiring research mainly in STEM fields, education, and science. From teaching to learning, Portal and its mechanics have been adapte...
The idea is to organise educational and recreational activities that contribute to combating loneliness among the elderly and to better understand these amazing animals. To reach this, AEPGA intends to organise donkey mediation activities that involve elderly people interacting with donkeys, aiming to mitigate several physical, mental and social health problems. Donkeys and the elderly, surprisingly, share a sl...
Sodium-glucose cotransporter 2 inhibitors (SGLT2i), originally developed as innovative antihyperglycemic agents, have demonstrated significant benefits in improving metabolic markers and protecting the kidneys and heart in patients with or without type 2 diabetes mellitus. The mechanisms behind these unexpected cardiorenal benefits cannot be attributed solely to improved glycemic control. Recent data suggest th...
Sodium-glucose cotransporter 2 inhibitors (SGLT2i), originally developed as innovative antihyperglycemic agents, have demonstrated significant benefits in improving metabolic markers and protecting the kidneys and heart in patients with or without type 2 diabetes mellitus. The mechanisms behind these unexpected cardiorenal benefits cannot be attributed solely to improved glycemic control. Recent data suggest th...
Paediatric neuroimaging is distinct from adult imaging, warranting dedicated approaches that take into account the singularities of this population in the selection of the appropriate imaging techniques for each phase of the normal development. The impact of ionising radiation exposure or contrast media usage need to be taken into account when planning or performing paediatric imaging, with risk versus benefit ...
Objective: To identify factors associated with C-peptide levels at the diagnosis of type 1 diabetes mellitus (T1DM). Material and Methods: Retrospective review of the clinical records of patients with newly diagnosed T1DM admitted to a Portuguese reference center between August 2010 and July 2019. Results: The study included 109 subjects, with a mean age at T1DM diagnosis of 8.6 years and 29.4% already showing ...
Background and objective Pediatric thyroid disease requiring surgery is rare. Thyroid nodules are a frequent indication for surgery and are mostly benign. However, up to 25% of cases can be malignant. In this study, we aimed to describe our center's experience with regard to pediatric thyroid surgery. Methods This was a retrospective transverse study involving pediatric patients who underwent thyroid surgery at...
Introduction: The incidence of childhood type 1 diabetes is increasing worldwide, especially in young children. According to international guidelines, continuous subcutaneous insulin infusion is the preferred method of insulin delivery for preschool children. This study aimed to evaluate the efficacy and safety of continuous subcutaneous insulin infusion treatment soon after diagnosis in preschool children with...
Made available in DSpace on 2022-04-29T08:00:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; Objective: To quantify the persistence of residues after endodontic retreatment related to the root canal obturation technique (lateral compaction or single cone) previously performed and the solvent used (xylol or Endosolv-R) in the cervical and root apical segment using digital radiograph. Materials a...