5 documents found, page 1 of 1
Design and proof of concept for targeted phage-based COVID-19 vaccination strat...
Staquicini, Daniela I.; Tang, Fenny H.F.; Markosian, Christopher; Yao, Virginia J.; Staquicini, Fernanda I.; Dodero-Rojas, EstebanMade available in DSpace on 2022-04-28T19:41:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-27; Development of effective vaccines against coronavirus disease 2019 (COVID-19) is a global imperative. Rapid immunization of the entire human population against a widespread, continually evolving, and highly pathogenic virus is an unprecedented challenge, and different vaccine approaches are being pursue...
PH and the Breast Cancer Recurrent Mutation D538G Affect the Process of Activat...
De Oliveira, Vinícius M.; Dias, Marieli M. G.; Avelino, Thayná M.; Videira, Natália B.; Da Silva, Fernando B. [UNESP]; Doratioto, Tábata R.Made available in DSpace on 2022-04-28T19:51:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-15; Estrogen receptor α (ERα) is a regulatory protein that can access a set of distinct structural configurations. ERα undergoes extensive remodeling as it interacts with different agonists and antagonists, as well as transcription activation and repression factors. Moreover, breast cancer tumors resistant ...
Drift-diffusion (DrDiff) framework determines kinetics and thermodynamics of tw...
Freitas, Frederico Campos; Lima, Angelica Nakagawa; Contessoto, Vinicius de Godoi [UNESP]; Whitford, Paul C.; Oliveira, Ronaldo Junio deMade available in DSpace on 2020-12-10T19:36:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-09-21; Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); National Science Foundation (NSF); National Science Foundation CAREER Award; The stochastic drift-diffus...
Distinguishing Biomolecular Pathways and Metastable States
Oliveira, Antonio B. [UNESP]; Yang, Huan; Whitford, Paul C.; Leite, Vitor B. P. [UNESP]Made available in DSpace on 2020-12-10T19:41:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-11-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); NSF CAREER award; Center for Theoretical Biological Physics - NSF; Protein folding occurs in a high di...
Diffusion of tRNA inside the ribosome is position-dependent
Yang, Huan; Bandarkar, Prasad; Horne, Ransom; Leite, Vitor B. P. [UNESP]; Chahine, Jorge [UNESP]; Whitford, Paul C.Made available in DSpace on 2019-10-06T17:19:39Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-28; National Science Foundation; In recent years, there has been a growing interest to quantify the energy landscape that governs ribosome dynamics. However, in order to quantitatively integrate theoretical predictions and experimental measurements, it is essential that one has a detailed understanding of t...