Made available in DSpace on 2020-12-10T17:40:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-08-01; Instituto Nacional de Ciencia e Tecnologia em Fisiologia Comparada (INCT-FisC); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Danish Research Council; Science without Borders program; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Vascular tone in the reptil-ian p...
The vasoactive proline-rich oligopeptide termed BPP-BrachyNH2 (H-WPPPKVSP-NH2) induces in vitro inhibitory activity of angiotensin I-converting enzyme (ACE) in rat blood serum. In the present study, the removal of N-terminal tryptophan or C-terminal proline from BPP-BrachyNH2 was investigated in order to predict which structural components are important or required for interaction with ACE. Furthermore, the tox...