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Cholinergic regulation along the pulmonary arterial tree of the South American ...

Filogonio, Renato; Sartori, Marina R. [UNESP]; Morgensen, Susie; Tavares, Driele; Campos, Rafael; Abe, Augusto S. [UNESP]; Taylor, Edwin W.

Made available in DSpace on 2020-12-10T17:40:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-08-01; Instituto Nacional de Ciencia e Tecnologia em Fisiologia Comparada (INCT-FisC); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Danish Research Council; Science without Borders program; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Vascular tone in the reptil-ian p...

Date: 2020   |   Origin: Oasisbr

Structure-function studies of BPP-BrachyNH 2 and synthetic analogues thereof wi...

Arcanjo, Daniel D.R.; Vasconcelos, Andreanne G.; Nascimento, Lucas A.; Mafud, Ana Carolina; Plácido, Alexandra; Alves, Michel M.M.

The vasoactive proline-rich oligopeptide termed BPP-BrachyNH2 (H-WPPPKVSP-NH2) induces in vitro inhibitory activity of angiotensin I-converting enzyme (ACE) in rat blood serum. In the present study, the removal of N-terminal tryptophan or C-terminal proline from BPP-BrachyNH2 was investigated in order to predict which structural components are important or required for interaction with ACE. Furthermore, the tox...


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