25 documents found, page 1 of 3
Metapleural- and postpharyngeal-gland secretions from workers of the ants Solen...
Cabrera, Aivlé; Williams, David; Hernández, José V.; Caetano, Flavio H. [UNESP]; Jaffe, KlausMade available in DSpace on 2022-04-28T18:55:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2004-12-01; Chemical analyses by GC-MS of the metapleural glands (MG) from workers of Solenopsis invicta and S. geminata revealed for the first time the chemical composition of these glands and showed small differences between the two species. The MG of both species contain oleic, stearic, linoleic, and palmitic ac...
Pathogenesis and virulence of Candida albicans and Candida glabrata
Henriques, Mariana; Williams, DavidFungal infections in humans have historically received comparatively less attention than those caused by bacteria and viruses. This may, in part, stem from the relative differences in infection prevalence. However, the more widespread use of immunosuppressive therapy, invasive surgery and medical devices in modern medicine has resulted in a more frequent occurrence of human fungal infection. There are a number ...
Extending the scope of pooled analyses of individual patient biomarker data fro...
Burke, Orlaith; Benton, Samantha; Szafranski, Pawel; von Dadelszen, Peter; Buhimschi, S. Catalin; Cetin, Irene; Chappell, Lucy; Figueras, FrancescMade available in DSpace on 2018-11-26T16:28:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-01-01; Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health; National Institute for Health Research; Background: A common challenge in medicine, exemplified in the analysis of biomarker data, is that large studies are ...
Candida albicans promotes invasion and colonisation of Candida glabrata in a re...
Alves, Carlos; Wei, Xiao-Qing; Silva, Sónia Carina; Azeredo, Joana; Henriques, Mariana; Williams, DavidThe principal aim of this study was to investigate the in vitro co-infection of a reconstituted human vaginal epithelium (RHVE) by Candida albicans and Candida glabrata. Methods The ability of both species to invade and colonise the RHVE was examined using species-specific peptide nucleic acid (PNA) probe hybridisation, confocal laser scanning microscopy (CLSM) and a novel qRT-PCR protocol for Candida quantific...
Colonization, invasion and damage of a reconstituted human oral epithelium by C...
Silva, Sónia Carina; Henriques, Mariana; Oliveira, Rosário; Williams, David; Azeredo, JoanaOral candisosis is a common problem in immunocompromised patients, and whilst Candida albicans is regarded as the principal cause of infection, other Candida species are increasingly being recognized as human pathogens. Moreover, relatively little is known about the role of Candida species in oral infections. Thus, this work aimed to examine Candida species infection of oral epithelium, and to assess their abil...
Candida biofilms and oral candidosis : treatment and prevention
Williams, David; Silva, Sónia Carina; Malic, Sladjana; Kuriyama, T.; Lewis, M. A. O.In recent years, there has been a significant increase in the incidence of human fungal infections (60). A number of factors have been implicated with this increase, but it is generally accepted that the main influences relate to the more widespread provision of new medical practices, such as immunosuppressive therapy and use of broad spectrum antibiotics, and invasive surgical procedures such as solid organ or...
Candida glabrata, Candida parapsilosis and Candida tropicalis : biology, epidem...
Silva, Sónia Carina; Negri, M.; Henriques, Mariana; Oliveira, Rosário; Williams, David; Azeredo, JoanaThe incidence of infections caused by Candida species (candidosis) has increased greatly over the past three decades, mainly due to the rise of the AIDS epidemic, an increasingly aged population, higher numbers of immunocompromised patients, and the more widespread use of indwelling medical devices. Candida albicans is the main cause of candidosis, however, non-Candida albicans Candida species such as Candida g...
Adherence and biofilm formation of non-Candida albicans Candida species
Silva, Sónia Carina; Negri, M.; Henriques, Mariana; Williams, David; Oliveira, Rosário; Azeredo, JoanaMost cases of candidosis have been attributed to Candida albicans, but recently non-Candida albicans Candida species have been identified as frequent human pathogens. Candida pathogenicity has been attributed to several factors, including adhesion to medical devices and/or host cells, biofilm formation, and secretion of hydrolytic enzymes (proteases, phospholipases, and haemolysins). Although ‘new’ Candida spec...
Biofilms formation by Candida tropicalis and Candida parapsilosis on an in vitr...
Silva, Sónia Carina; Henriques, Mariana; Oliveira, Rosário; Azeredo, Joana; Williams, DavidThe primary event in Candida infection is the colonization of host mucosal surfaces, often leading to the formation of biofilms. Most cases of candidosis have been attributed to Candida albicans, however, recently, non-Candida albicans Candida species have been identified as frequent pathogens of humans. Given the clinical importance of biofilm growth, the aim of this work was to study the biofilm formation by ...
The role of Candida species in colonization, invasion and damage of an in vitro...
Silva, Sónia Carina; Henriques, Mariana; Oliveira, Rosário; Williams, David; Azeredo, JoanaThe role of Candida species in colonization, invasion and damage of an in vitro r Oral candisosis is a common problem in immunocompromised patients, and whilst Candida albicans is regarded as the principal cause of infection, other Candida species are increasingly being recognized as human pathogens. Moreover, relatively little is known about the role of Candida species in oral infections. Thus, this work aimed...