20 documents found, page 1 of 2
Performance of the dipstick screening test as a predictor of negative urine cul...
Marques,Alexandre Gimenes; Doi,André Mario; Pasternak,Jacyr; Damascena,Márcio dos Santos; França,Carolina Nunes; Martino,Marinês Dalla ValleABSTRACT Objective To investigate whether the urine dipstick screening test can be used to predict urine culture results. Methods A retrospective study conducted between January and December 2014 based on data from 8,587 patients with a medical order for urine dipstick test, urine sediment analysis and urine culture. Sensitivity, specificity, positive and negative predictive values were determined and ROC curve...
Robot-assisted needle insertion for venous catheterization
Pasternak,JacyrVein access can be challenging for a variety of patients. The development of robots-assisted central or peripheral veins puncture would facilitate life of health professionals and patients. New robots are under development for this purpose and probably they will become available for practical use in the near future. These techniques may decrease significantly the cost of medicine, which currently uses less info...
Cardiac stem cells and their clinical use
Pasternak,JacyrStem cells have been used to correct the ravages of atherosclerotic heart disease and other diseases that involve acute deficit of myocardial muscle, such as myocarditis. Previous attempts at using bone marrow derived from stem cells have not been particularly successful. New technologies using cardiac stem cells seem to offer a better perspective of obtaining such regeneration.
SeptiFast for diagnosis of sepsis in severely ill patients from a Brazilian hos...
Sitnik,Roberta; Marra,Alexandre Rodrigues; Petroni,Roberta Cardoso; Ramos,Ozires Pereira Santos; Martino,Marinês Dalla Valle; Pasternak,JacyrObjective To test and validate a multiplex real-time polymerase chain reaction method for bloodstream infections, as well as to compare the results with conventional blood culture.Methods A total of 114 consecutive patients with clinical evidence of sepsis were submitted to blood culture and LightCycler™ SeptiFast tests.Results More positive specimens (23; 20.2%) were detected using the LightCycler™ SeptiFast t...
Vacina contra herpes-zóster
Pasternak,JacyrA vacinação contra o herpes-zóster é feita com altas doses de vírus vivo da varicela/zóster atenuado. A vacina é bem tolerada e tem poucos efeitos colaterais, sendo o mais comum a dor no local de vacinação. Complicações vacinais podem ocorrer, particularmente em quem já teve queratite ou uveíte por herpes zóster. A vacina pode prevenir uma doença de baixa mortalidade mas de morbidade não desprezível.
Meningite por Haemophilus influenzae tipo f
Cardoso,Marta Pessoa; Pasternak,Jacyr; Giglio,Alfredo Elias; Casagrande,Rejane Rimazza Dalberto; Troster,Eduardo JuanCom o declínio da taxa de infecções causadas pelo Haemophilus influenzae tipo b após a ampla introdução da vacina, sorotipos não-b devem ser considerados agentes patogênicos potenciais em crianças menores de 5 anos com doença invasiva. Relatamos um caso de meningite por Haemophilus influenzae tipo f em um lactente imunocompetente de 1 ano. O agente foi identificado em líquido cefalorraquidiano e hemocultura. A ...
MALDI-TOF MS in the clinical microbiology laboratory
Mimica,Marcelo Jenne; Martino,Marines Dalla Valle; Pasternak,JacyrTraditional methods for microbial identification are often very laborious and time consuming. A new mass spectrometry based technique, matrix-assisted laser desorption ionization-time of flight (MALDI-TOF), has been described as a rapid, practical and low-cost method for this purpose. In this article, primary and possible future applications of this tool are briefly discussed.
New methods of microbiological identification using MALDI-TOF
Pasternak,JacyrRapid diagnosis of pathogens is decisive to guarantee adequate therapy in infections: culture methods are precise and sensitive, but rather slow. New resources are available to enable faster diagnosis, and the most promising is MALDI-TOF technology: mass spectrometry applied to microbiological diagnosis. Times as fast as 10 to 15 minutes to etiological diagnosis are possible after a positive blood culture resul...
Adaptação experimental de uma cepa de influenza H5HA confere transmissão por go...
Pasternak,JacyrAnalisa-se o papel - se houver algum - da censura a artigos científicos, alicerçada na publicação do trabalho que mostra ser possível a modificação genética do vírus H5N1 da influenza aviária, tornando-o mais transmissível entre mamíferos, que foi seguida de muito alvoroço e muita discussão ética.
Not all that shines is cancer: pulmonary cryptococcosis mimicking lymphoma in [...
Hamerschlak,Nelson; Pasternak,Jacyr; Wagner,Jairo; Perini,Guilherme FleuryWe report of a case of pulmonary cryptococcosis mimicking lymphoma in a positron emission tomography (FDG-PET) scan. A 62-year old man with diffuse large B-cell lymphoma had complete resolution of abdominal and pulmonary lesions after three cycles of rituximab-based chemotherapy (R-CHOP). However, FDG-PET showed new pulmonary nodules, suggesting active lymphoma. Chronic inflammatory granuloma was seen in the hi...