3 documents found, page 1 of 1
Resistance of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braz...
Giudice, Ângela; Camada, Ilza; Leopoldo, Paulo de Tarso Gonçalves; Pereira, Júlia M. B.; Rilley, Lee; Wilson, Mary; Ho, JohnBACKGROUND: Nitric oxide (NO•) plays a pivotal role as a leishmanicidal agent in mouse macrophages. NO• resistant Escherichia coli and Mycobacterium tuberculosis have been associated with a severe outcome of these diseases. METHODS: In this study we evaluated the in vitro toxicity of nitric oxide for the promastigote stages of Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis parasites, ...
Resistance of Leishmania (Viannia) braziliensis to nitric oxide: correlation wi...
Souza, Anselmo; Giudice, Ângela; Pereira, Júlia M. B.; Guimarães, Luiz Henrique Santos; Jesus, Amélia Maria Ribeiro de; Moura, Tatiana Rodrigues deBACKGROUND: Nitric oxide (NO) produced in macrophages plays a pivotal role as a leishmanicidal agent. A previous study has demonstrated that 20% of the L. (V.) braziliensis isolated from initial cutaneous lesions of patients from the endemic area of Corte de Pedra, Bahia, Brazil, were NO resistant. Additionally, 5 to 11% of the patients did not respond to three or more antimony treatments" (refractory patients)...
Threat of Dengue to Blood Safety in Dengue-Endemic Countries
Wilson, Mary