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Gene Silencing via PDA/ERK2-siRNA-Mediated Electrospun Fibers for Peritendinous...
Liu, S; Wu, F; Gu, S; Wu, T; Chen, S; Chen, S; Wang, C; Huang, G; Jin, T; Cui, W; Sarmento, B; Deng, L; Fan, CSustained delivery of small interfering RNA (siRNA) is a challenge in gene silencing for managing gene-related disorders. Although nanoparticle-mediated electrospun fibers enable sustainable gene silencing, low efficiency, loss of biological activity, toxicity issues, and complex electrospinning techniques are all bottlenecks of these systems. Preventing peritendinous adhesion is crucial for their successful us...
Date: 2019
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Origin: Repositório Aberto da Universidade do Porto