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Endothelial cell invasion is controlled by dactylopodia

Figueiredo, Ana; Barbacena, Pedro; Russo, Ana; Vaccaro, Silvia; Ramalho, Daniela; Pena, Andreia; Lima, Aida Pires; Rua Ferreira, Rita; Fidalgo, Marta

Sprouting angiogenesis is fundamental for development and contributes to cancer, diabetic retinopathy, and cardiovascular diseases. Sprouting angiogenesis depends on the invasive properties of endothelial tip cells. However, there is very limited knowledge on how tip cells invade into tissues. Here, we show that endothelial tip cells use dactylopodia as the main cellular protrusion for invasion into nonvascular...


Textual organizers and text plan: the “e” form

Rosa, Rute; Fidalgo, Marta; Gonçalves, Matilde; Leal, Audria; Jorge, Noémia

Situated within the theoretical framework of Sociodiscursive Interactionism, this paper focuses on the role of textual organisers as elements that contribute to the identification of the text plan. The notion of textual organisers has been addressed by various authors and there are still several terminological variations and different categorisation proposals. Based on a qualitative textual analysis, this artic...


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