4 documents found, page 1 of 1
Gellan gum injectable hydrogels for cartilage tissue engineering applications: ...
Oliveira, J. T.; Santos, T. C.; Martins, L.; Picciochi, R.; Marques, A. P.; Castro, António G.; Neves, N. M.; Mano, J. F.; Reis, R. L.Gellan gum is a polysaccharide that we have previously proposed for applications in the cartilage tissue engineering field. In this work, gellan gum hydrogels were tested for their ability to be used as injectable systems using simple processing methods, able to deliver and maintain chondrocytes by in situ gelation, and support cell viability and production of extracellular matrix (ECM). Rheological measurement...
Gellan gum: a new biomaterial for cartilage tissue engineering applications
Oliveira, J. T.; Martins, L.; Picciochi, R.; Malafaya, P. B.; Sousa, R. A.; Neves, N. M.; Mano, J. F.; Reis, R. L.Gellan gum is a polysaccharide manufactured by microbial fermentation of the Sphingomonas paucimobilis microorganism, being commonly used in the food and pharmaceutical industry. It can be dissolved in water, and when heated and mixed with mono or divalent cations, forms a gel upon lowering the temperature under mild conditions. In this work, gellan gum hydrogels were analyzed as cells supports in the context o...
Injectable gellan gum hydrogels as supports for cartilage tissue engineering ap...
Oliveira, J. T.; Picciochi, R.; Santos, T. C.; Martins, L.; Pinto, L. G.; Malafaya, P. B.; Sousa, R. A.; Marques, A. P.; Castro, A. G.; Mano, J. F.Gellan gum is an extracellular microbial polysaccharide from Sphingomonas paucimobilis that forms a firm and transparent gel in the presence of metallic ions. This hydrogel presents some interesting features that allow its use as a cell encapsulating support, or as an in vivo injectable system. In this work, the usefulness of gellan gum hydrogels as supports for cartilage tissue engineering applications was sho...
Injectable gellan gum hydrogels as supports for cartilage tissue engineering ap...
Oliveira, J. T.; Picciochi, R.; Santos, T. C.; Martins, L.; Pinto, L. G.; Malafaya, P. B.; Sousa, R. A.; Marques, A. P.; Castro, A. G.; Mano, J. F.Gellan gum is an extracellular microbial polysaccharide from Sphingomonas paucimobilis that forms a firm and transparent gel in the presence of metallic ions. This hydrogel presents some in- teresting features that allow its use as a cell encapsulating support, or as an in vivo injectable system. In this work, the usefulness of gellan gum hydrogels as supports for cartilage tissue engineering applications was s...