The impact of nanotechnology on the exponential growth of several research areas, particularly nanomedicine, is undeniable. The ability to deliver active molecules to the desired site could significantly improve the efficiency of medical treatments. One of the nanocarriers developed which has drawn researchers’ attention are cubosomes, which are nanosized dispersions of lipid bicontinuous cubic phases in water,...
[Excerpt] Cubosomes are nano-sized dispersions of bicontinuous cubic phases in water, ideal to deliver bioactive molecules in therapeutic applications [1]. Typically they are prepared either by fragmenting the cubic phase in excess water using high energy input, or using solvent-shifting approaches [2]. In both cases, poor experimental control at the micron-scale (e.g. poor control on concentration gradients), ...
Made available in DSpace on 2022-04-29T08:45:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-10-01; Aim: To compare cardiac autonomic modulation in early- versus advanced-stage breast cancer patients before any type of cancer treatment and investigate associated factors. Methods and results: This cross-sectional study included women (30–69 years old) with primary diagnosis of breast cancer and women w...
Made available in DSpace on 2022-04-29T08:31:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Individuals with Duchenne Muscular Dystrophy (DMD) have an impairment of cardiac autonomic function categorized by parasympathetic reduction and sympathetic predominance. ...
Made available in DSpace on 2022-10-10T13:56:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-08-05. Added 1 bitstream(s) on 2022-10-10T15:40:15Z : No. of bitstreams: 1 S0066-782X2022005012202.pdf: 557420 bytes, checksum: 79d9459487fae0c0975b233b00b943ea (MD5); Universidade Estadual Paulista (UNESP), Faculdade de Ciências e Tecnologias; Universidade Estadual Paulista (UNESP), Centro de Estudos do Siste...
Made available in DSpace on 2022-04-29T07:11:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-08-27; Abstract. Introduction. Hydration plays a key role in the physiological maintenance required by exercise. Objective. To evaluate the behavior of heart rate (HR), systolic (SBP) and diastolic (DBP) blood pressure, pulse oxygen saturation (SpO2) and respiratory rate (RR) of young people during and after p...
Made available in DSpace on 2022-04-29T07:12:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-09-25; Background: In prolonged exercise, the state of hypohydration due to sweating raises physiological stress and induces a drop in sports performance. However, the impact of water intake in cardiorespiratory parameters when administered during and after physical activity has not been well studied. This stu...
Made available in DSpace on 2022-04-29T07:12:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-10-28; Background: Chronic exposure to musical auditory stimulation has been reported to improve cardiac autonomic regulation. However, it is not clear if music acutely influences it in response to autonomic tests. We evaluated the acute effects of music on heart rate variability (HRV) responses to the postura...
Made available in DSpace on 2022-05-01T09:47:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Background: Analysis of autonomic modulation after postural change may inform the prognosis and guide treatment in different populations. However, this has been insufficiently explored among adolescents with Duchenne muscular dystrophy (DMD). Objective: To investigate autonomic modulation at rest and in...
Made available in DSpace on 2022-05-01T11:07:39Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-23; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Introduction: Due to functional and autonomic difficulties faced by individuals with Duchenne Muscular Dystrophy (DMD), the use of assistive technology is critical to provide or facilitate functional abilities. The key objective was to inves...