3 documents found, page 1 of 1
Efeito do Fucoidam de Fucus vesiculosus em um modelo experimental de artrite re...
Xavier, Caroline Addison CarvalhoCoordenação de Aperfeiçoamento de Pessoal de Nível Superior; Rheumatoid arthritis (RA) is systemic auto imune disorder. It is caracterized by chronic inflammation of joints leading to progressive erosion of cartilage and bone. We investigated the effect of the administration of fucoidan, sulfated polysaccharides, from algae Fucus vesiculosus in the acute (6h) in zymosan-induced arthritis (AZy). Wistar rats (180...
Estudo do efeito da atorvastatina na mucosites oral induzida por 5-fluorouracil...
Xavier, Caroline Addison CarvalhoOral mucositis (OM) is a frequent side effect and dose-limiting of cancer therapy, characterized by intense inflammatory mucosal reaction and formation of ulcers in oropharyngeal cavity. The aim of this study was to evaluate the effect of atorvastatin (ATV) – cholesterol lowering drug with anti-inflammatory activity - in oral mucositis induced by 5-fluorouracil (5-FU) in Golden Sirian hamsters. Oral mucositis w...
Ecstasy (MDMA): pharmacological and toxic effects, mechanism of action and clin...
Xavier, Caroline Addison Carvalho; Lobo, Patrícia Leal Dantas; Fonteles, Marta Maria de França; Vasconcelos, Silvânia Maria Mendes deBACKGROUND: The consumption of the amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) by young people increased in the past years. OBJECTIVES: To conduct a literature review on the pharmacology of MDMA and particularly with respect to the putative mechanism of action implicated in the acute and long-term toxicity and neurotoxic effects. METHODS: A literature review using the key words: 3,4...